The chemical reactivity of membrane lipids

G Duché, JM Sanderson - Chemical Reviews, 2024 - ACS Publications
It is well-known that aqueous dispersions of phospholipids spontaneously assemble into
bilayer structures. These structures have numerous applications across chemistry and …

Structural and functional consequences of reversible lipid asymmetry in living membranes

M Doktorova, JL Symons, I Levental - Nature chemical biology, 2020 - nature.com
Maintenance of lipid asymmetry across the two leaflets of the plasma membrane (PM)
bilayer is a ubiquitous feature of eukaryotic cells. Loss of this asymmetry has been widely …

Free radicals and polyphenols: The redox chemistry of neurodegenerative diseases

S Losada-Barreiro, C Bravo-Diaz - European journal of medicinal chemistry, 2017 - Elsevier
The oxidation of bioorganic materials by air and, particularly, the oxidative stress involved in
the cell loss and other pathologies associated with neurodegenerative diseases (NDs) are …

In vitro release kinetics model fitting of liposomes: An insight

A Jain, SK Jain - Chemistry and physics of lipids, 2016 - Elsevier
Liposomes are emerging cargoes for bioactive delivery owing to their widely accepted
biocompatible and biodegradable nature. It is always a challenge to control the release of …

Structure of lipid nanoparticles containing siRNA or mRNA by dynamic nuclear polarization-enhanced NMR spectroscopy

J Viger-Gravel, A Schantz, AC Pinon… - The Journal of …, 2018 - ACS Publications
Here, we show how dynamic nuclear polarization (DNP) NMR spectroscopy experiments
permit the atomic level structural characterization of loaded and empty lipid nanoparticles …

Mimicking the mammalian plasma membrane: An overview of lipid membrane models for biophysical studies

A Luchini, G Vitiello - Biomimetics, 2020 - mdpi.com
Cell membranes are very complex biological systems including a large variety of lipids and
proteins. Therefore, they are difficult to extract and directly investigate with biophysical …

Polyphenolic antioxidants in lipid emulsions: Partitioning effects and interfacial phenomena

M Costa, S Losada-Barreiro, F Paiva-Martins… - Foods, 2021 - mdpi.com
The autoxidation of lipids in complex systems such as emulsions or biological membranes,
although known to occur readily and to be associated with important pathological events, is …

Multiscale lipid membrane dynamics as revealed by neutron spectroscopy

VK Sharma, E Mamontov - Progress in Lipid Research, 2022 - Elsevier
The plasma membrane is one of the principal structural components of the cell and,
therefore, one of the key components of the cellular life. Because the membrane's dynamics …

Vesicle formation mechanisms: an overview

C Has, S Pan - Journal of liposome research, 2021 - Taylor & Francis
Vesicle structures primarily embody spherical capsules composed of a single or multiple
bilayers, entrap** a pool of aqueous solution in their interior. The bilayers can be …

Shape matters in protein mobility within membranes

F Quemeneur, JK Sigurdsson, M Renner… - Proceedings of the …, 2014 - pnas.org
The lateral mobility of proteins within cell membranes is usually thought to be dependent on
their size and modulated by local heterogeneities of the membrane. Experiments using …