Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …

The development of animal embryos is initially directed by maternal gene products. Then,
during the maternal-to-zygotic transition (MZT), developmental control is handed to the …

Embryogenesis depends on a highly coordinated cascade of genetically encoded events. In
animals, maternal factors contributed by the egg cytoplasm initially control development …

3-3 proteins are highly conserved regulatory proteins that interact with hundreds of
structurally diverse clients and act as central hubs of signaling networks. However, how 14-3 …

During the maternal-to-zygotic transition (MZT), multiple mechanisms precisely control
massive decay of maternal mRNAs. N 6-methyladenosine (m 6 A) is known to regulate …

In mammals, maternal-to-zygotic transition (MZT), or oocyte-to-embryo transition, begins with
oocyte meiotic resumption due to the sequential translational activation and destabilization …

Germ granules are hallmarks of all germ cells. Early ultrastructural studies in Drosophila first
described these membraneless granules in the oocyte and early embryo as filled with …

Because maturing oocytes and early embryos lack appreciable transcription,
posttranscriptional regulatory processes control their development. To better understand this …

The maternal-to-zygotic transition (MZT) is a process that occurs in animal embryos at the
earliest developmental stages, during which maternally deposited mRNAs and other …

Spatiotemporal gene regulation is often driven by RNA-binding proteins that harbor long
intrinsically disordered regions in addition to folded RNA-binding domains. We report that …