Crohn's disease is a chronic granulomatous ileocolitis, of unknown etiology, which generally
affects the patient during the prime of life. Medical treatment is supportive at best, and …

Crohn's disease (CD) is an inflammatory bowel disease (IBD) of unknown aetiology.
Genetically engineered rodent models showed that IBDs are immunologically mediated and …

Anorectal myectomy was performed in 62 patients suffering from symptoms attrib¬ uted to
ineffective colonic motility. Indications for surgery rested on the presence of one or more of …

As the infection cycle of adherent-invasive E. coli could depend upon the ability of these
pathogenic bacteria to colonize the gastrointestinal tract of genetically predisposed Crohn's …

Ulcerative colitis and granulomatous colitis are distinct entities, but up to 10 percent of
colectoiny specimens remain unclassified. Ulcerative colitis is liriniarily a inucosal disease …

We have greatly increased our understanding of the genetics of inflammatory bowel disease
(IBD) in the last decade; however, migrant studies highlight the importance of environment in …

Conclusions In conclusion, there is a shift in the population of IgG glycoforms towards those
with a higher content of agalactosyl biantennary N-linked oligosaccharides in active …

Pilot studies were done to assess the pathogenicity of a Mycobacterium which had been
recovered from the diseased ileum of a patient with Crohn's disease. In four separate …

In order to study the effect of clofazimine, a powerful antimycobacterial and antiinflammatory
agent, 49 patients with active Crohn's disease were randomized to either corticosteroids …

We pursued the possibility that Mycobacterium kansasii might be an aetiological agent in
Crohn's disease by carrying out a trial of treatment with antimycobacterial drugs. Twenty …