Cholesterol homeostasis is vital for proper cellular and systemic functions. Disturbed
cholesterol balance underlies not only cardiovascular disease but also an increasing …

Cholesterol is an essential component of animal cell membranes, and its concentration is
tightly controlled by a feedback system that operates at transcriptional and …

Cholesterol is an essential structural component in the cell membranes of most vertebrates.
The biophysical properties of cholesterol and the enzymology of cholesterol metabolism …

Cholesterol is an essential structural component of membranes that contributes to
membrane integrity and fluidity. Cholesterol homeostasis plays a critical role in the …

Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

Cholesterol is an essential lipid and its synthesis is nutritionally and energetically costly,. In
mammals, cholesterol biosynthesis increases after feeding and is inhibited under fasting …

Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that
regulate lipid biosynthesis and adipogenesis by controlling the expression of several …

Cholesterol synthesis in animals is controlled by the regulated transport of sterol regulatory
element-binding proteins (SREBPs) from the endoplasmic reticulum to the Golgi, where the …

Cholesterol is an essential component of mammalian cell membranes and is required for
proper membrane permeability, fluidity, organelle identity, and protein function. Cells …

Cholesterol is a lipid molecule that plays an essential role in a number of biological
processes, both physiological and pathological. It is an essential structural constituent of cell …