Plant pathogen forensics: capabilities, needs, and recommendations

J Fletcher, C Bender, B Budowle… - Microbiology and …, 2006 - Am Soc Microbiol
SUMMARY A biological attack on US crops, rangelands, or forests could reduce yield and
quality, erode consumer confidence, affect economic health and the environment, and …

Asymmetric directional mutation pressures in bacteria

JR Lobry, N Sueoka - Genome biology, 2002 - Springer
Background When there are no strand-specific biases in mutation and selection rates (that
is, in the substitution rates) between the two strands of DNA, the average nucleotide …

Single nucleotide polymorphism–based validation of exonic splicing enhancers

WG Fairbrother, D Holste, CB Burge, PA Sharp - PLoS biology, 2004 - journals.plos.org
Because deleterious alleles arising from mutation are filtered by natural selection, mutations
that create such alleles will be underrepresented in the set of common genetic variation …

[PDF][PDF] The Impact of the Transversion/Transition Ratio on the Optimal Genetic Code Graph Partition.

DA Aloqalaa, DR Kowalski, P Blazej, M Wnetrzak… - …, 2019 - scitepress.org
The standard genetic code (SGC) is a system of rules ascribing 20 amino acids and stop
translation signal to 64 codons, ie triplets of nucleotides. It was proposed that the structure of …

Optimization of amino acid replacement costs by mutational pressure in bacterial genomes

P Błażej, D Mackiewicz, M Grabińska, M Wnętrzak… - Scientific reports, 2017 - nature.com
Mutations are considered a spontaneous and random process, which is important
component of evolution because it generates genetic variation. On the other hand, mutations …

Optimization of mutation pressure in relation to properties of protein-coding sequences in bacterial genomes

P Błażej, B Miasojedow, M Grabińska, P Mackiewicz - PloS one, 2015 - journals.plos.org
Most mutations are deleterious and require energetically costly repairs. Therefore, it seems
that any minimization of mutation rate is beneficial. On the other hand, mutations generate …

Optimisation of asymmetric mutational pressure and selection pressure around the universal genetic code

P Mackiewicz, P Biecek, D Mackiewicz, J Kiraga… - International Conference …, 2008 - Springer
One of hypotheses explaining the origin of the genetic code assumes that its evolution has
minimised the deleterious effects of mutations in coded proteins. To estimate the level of …

Correspondence between mutation and selection pressure and the genetic code degeneracy in the gene evolution

M Dudkiewicz, P Mackiewicz, A Nowicka… - Future Generation …, 2005 - Elsevier
There are three main elements deciding about the effect of mutations on the protein coding
sequences—the type of the substitution of nucleotide, the selection for the function of the …

[PDF][PDF] Microbial forensics: are we going on right path for management of crops biosecurity in Pakistan?

I Aziz, S Ali, Z Rehman, S Aman… - Advancements in Life …, 2024 - als-journal.com
Microbial forensics is the discipline which is applying the scientific methods for analysis of
bioterrorism and/or accidental release of a biological agent and toxins. In present review the …

DNA sequence representation by trianders and determinative degree of nucleotides

D Diana, D Steven - Journal of Zhejiang University Science B, 2005 - Springer
A new version of DNA walks, where nucleotides are regarded unequal in their contribution
to a walk is introduced, which allows us to study thoroughly the “fine structure” of nucleotide …