[HTML][HTML] The epidemiology of Alzheimer's disease modifiable risk factors and prevention

XX Zhang, Y Tian, ZT Wang, YH Ma, L Tan… - The journal of prevention …, 2021 - Elsevier
Mild Alzheimer's disease is the leading cause of dementia, accounting for 50–70% of cases.
Alzheimer's disease is an irreversible neurodegenerative disease, which affects daily life …

Physical activity for cognitive health promotion: An overview of the underlying neurobiological mechanisms

C Chen, S Nakagawa - Ageing Research Reviews, 2023 - Elsevier
Physical activity is one of the modifiable factors of cognitive decline and dementia with the
strongest evidence. Although many influential reviews have illustrated the neurobiological …

[HTML][HTML] International exercise recommendations in older adults (ICFSR): expert consensus guidelines

M Izquierdo, RA Merchant, JE Morley, SD Anker… - The journal of nutrition …, 2021 - Springer
The human ageing process is universal, ubiquitous and inevitable. Every physiological
function is being continuously diminished. There is a range between two distinct phenotypes …

Exercise benefits on Alzheimer's disease: State-of-the-science

PL Valenzuela, A Castillo-García, JS Morales… - Ageing research …, 2020 - Elsevier
Although there is no unanimity, growing evidence supports the value of regular physical
exercise to prevent Alzheimer's disease as well as cognitive decline in affected patients …

Associations between handgrip strength and dementia risk, cognition, and neuroimaging outcomes in the UK Biobank cohort study

KA Duchowny, SF Ackley, WD Brenowitz… - JAMA network …, 2022 - jamanetwork.com
Importance The associations between muscle strength and cognitive outcomes have
sparked interest in interventions that increase muscle strength for prevention of dementia …

Overlooked cases of mild cognitive impairment: Implications to early Alzheimer's disease

M Mian, J Tahiri, R Eldin, M Altabaa, U Sehar… - Ageing Research …, 2024 - Elsevier
Mild cognitive impairment (MCI) marks the initial phase of memory decline or other cognitive
functions like language or spatial perception, while individuals typically retain the capacity to …

[HTML][HTML] Exerkines and long-term synaptic potentiation: Mechanisms of exercise-induced neuroplasticity

WAJ Vints, O Levin, H Fujiyama, J Verbunt… - Frontiers in …, 2022 - Elsevier
Physical exercise may improve cognitive function by modulating molecular and cellular
mechanisms within the brain. We propose that the facilitation of long-term synaptic …

The effects of resistance exercise on cognitive function, amyloidogenesis, and neuroinflammation in Alzheimer's disease

CV Azevedo, D Hashiguchi, HC Campos… - Frontiers in …, 2023 - frontiersin.org
With the increasing prevalence of Alzheimer's disease (AD) and difficulties in finding
effective treatments, it is essential to discover alternative therapies through new approaches …

Exercise interventions preserve hippocampal volume: A meta‐analysis

KA Wilckens, CM Stillman, AM Waiwood… - …, 2021 - Wiley Online Library
Hippocampal volume is a marker of brain health and is reduced with aging and neurological
disease. Exercise may be effective at increasing and preserving hippocampal volume …

Comparative efficacy of various exercise interventions on depression in older adults with mild cognitive impairment: a systematic review and network meta-analysis

Q Liu, W Ni, L Zhang, M Zhao, X Bai, S Zhang… - Ageing research …, 2023 - Elsevier
Background Exercise is a promising nonpharmacological treatment for improving
depression in older adults with MCI, but it is unclear which exercises are most effective. The …