Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …

Cachexia, a systemic wasting condition, is considered a late consequence of diseases,
including cancer, organ failure, or infections, and contributes to significant morbidity and …

Drug resistance represents a major obstacle in cancer management, and the mechanisms
underlying stress adaptation of cancer cells in response to therapy-induced hostile …

Skeletal muscle‐related symptoms are common in both acute coronavirus disease (Covid)‐
19 and post‐acute sequelae of Covid‐19 (PASC). In this narrative review, we discuss …

Mitochondria control cellular fate by various mechanisms and are key drivers of cellular
metabolism. Although the main function of mitochondria is energy production, they are also …

Peroxisome proliferator‐activated receptor‐γ coactivator (PGC)‐1α is a transcriptional
coactivator described as a master regulator of mitochondrial biogenesis and function …

The ribotoxic stress response (RSR) is a signaling pathway in which the p38-and c-Jun N-
terminal kinase (JNK)–activating mitogen-activated protein kinase kinase kinase (MAP3K) …

This narrative review presents a biological rationale and evidence to describe how the
preoperative condition of the patient contributes to postoperative morbidity. Any preoperative …

Biomarker discovery and implementation are at the forefront of the precision medicine
movement. Modern advances in the field of metabolomics afford the opportunity to readily …

Ageing is a crucial risk factor for Alzheimer's disease (AD) and is characterised by systemic
changes in both intracellular and extracellular microenvironments that affect the entire body …