The small (40S) subunit of eukaryotic ribosomes is believed to bind initially at the capped 5'-
end of messenger RNA and then migrate, stop** at the first AUG codon in a favorable …

Fibroblast growth factors (FGFs) are small polypeptide growth factors, all of whom share in
common certain structural characteristics, and most of whom bind heparin avidly. Many …

Fibroblast growth factors (FGFs) are essential molecules for mammalian development. The
nine known FGF ligands and the four signaling FGF receptors (and their alternatively spliced …

Increasingly, primary hypertension is being considered a syndrome and not a disease, with
the individual causes (diseases) having a common sign—an elevated blood pressure. To …

Signaling pathways that mediate the normal functions of growth factors are commonly
subverted in cancer. Oncogenes identified by a variety of approaches have been shown to …

FGF signaling plays a ubiquitous role in human biology as a regulator of embryonic
development, homeostasis and regenerative processes. In addition, aberrant FGF signaling …

Publisher Summary The fibroblast growth factors (FGFs) constitute a family of closely related
polypeptide mitogens. There are seven members of this family, identified on the basis of …

A recurrent observation in the development of the nervous system is the generation of
neurons followed by their large scale elimination. This phenomenon, usually referred to as …

Publisher Summary The family of fibroblast growth factors (FGF) is the largest family of
growth factors involved in soft–tissue growth and regeneration. The FGF family includes …

The fibroblast or heparin-binding growth factors (HBGFs) are thought to be modulators of
cell growth and migration, angiogenesis, wound repair, neurite extension, and mesoderm …