Probiotics to improve the gut microbiome in premature infants: are we there yet?

EM Mercer, MC Arrieta - Gut microbes, 2023 - Taylor & Francis
Gut microbiome maturation in infants born prematurely is uniquely influenced by the
physiological, clinical, and environmental factors surrounding preterm birth and early life …

Therapeutic potential of gut microbiota and its metabolite short-chain fatty acids in neonatal necrotizing enterocolitis

NA Alsharairi - Life, 2023 - mdpi.com
Short chain fatty acids (SCFAs), the principle end-products produced by the anaerobic gut
microbial fermentation of complex carbohydrates (CHO) in the colon perform beneficial roles …

Impact of milk secretor status on the fecal metabolome and microbiota of breastfed infants

A Wang, A Diana, S Rahmannia, RS Gibson… - Gut …, 2023 - Taylor & Francis
Maternal secretor status has been shown to be associated with the presence of specific
fucosylated human milk oligosaccharides (HMOs), and the impact of maternal secretor …

Milk oligosaccharide-driven persistence of Bifidobacterium pseudocatenulatum modulates local and systemic microbial metabolites upon synbiotic treatment in …

JA Larke, BE Heiss, AM Ehrlich, DH Taft, HE Raybould… - Microbiome, 2023 - Springer
Background Bifidobacteria represent an important gut commensal in humans, particularly
during initial microbiome assembly in the first year of life. Enrichment of Bifidobacterium is …

The impact of gut microbiota on morbidities in preterm infants

MY Lai, YH Chang, CC Lee… - … Journal of Medical …, 2024 - Wiley Online Library
The gut microbiota undergoes substantial development from birth, and its development in
the initial years of life has a potentially lifelong effect on the health of the individual …

[HTML][HTML] Microbiome therapeutics for food allergy

DA Chernikova, MY Zhao, JP Jacobs - Nutrients, 2022 - mdpi.com
The prevalence of food allergies continues to rise, and with limited existing therapeutic
options there is a growing need for new and innovative treatments. Food allergies are, in a …

A systematic review of associations between gut microbiota composition and growth failure in preterm neonates

LL Neves, AB Hair, GA Preidis - Gut Microbes, 2023 - Taylor & Francis
Growth failure is among the most prevalent and devastating consequences of prematurity.
Up to half of all extremely preterm neonates struggle to grow despite modern nutrition …

Translating neonatal microbiome science into commercial innovation: metabolism of human milk oligosaccharides as a basis for probiotic efficacy in breast-fed infants

DA Mills, JB German, CB Lebrilla, MA Underwood - Gut Microbes, 2023 - Taylor & Francis
For over a century, physicians have witnessed a common enrichment of bifidobacteria in the
feces of breast-fed infants that was readily associated with infant health status. Recent …

Analysis of the fecal metabolomic profile in breast vs. Different formula milk feeding in late preterm infants

G De Bernardo, G D'Urso, S Spadarella, M Giordano… - Metabolites, 2024 - mdpi.com
Human milk is the gold standard for infant nutrition, but when it is not available or insufficient
to satisfy the needs of the infant, formula milk is proposed as an effective substitute. A …

Effects of early postnatal life nutritional interventions on immune-microbiome interactions in the gastrointestinal tract and implications for brain development and …

JA Mullaney, NC Roy, C Halliday, W Young… - Frontiers in …, 2022 - frontiersin.org
The gastrointestinal (GI) microbiota has co-evolved with the host in an intricate relationship
for mutual benefit, however, inappropriate development of this relationship can have …