Engineering bacteria as interactive cancer therapies

CR Gurbatri, N Arpaia, T Danino - Science, 2022 - science.org
With increasing evidence that microbes colonize tumors, synthetic biology tools are being
leveraged to repurpose bacteria as tumor-specific delivery systems. These engineered …

Engineered living materials for sustainability

B An, Y Wang, Y Huang, X Wang, Y Liu, D Xun… - Chemical …, 2022 - ACS Publications
Recent advances in synthetic biology and materials science have given rise to a new form of
materials, namely engineered living materials (ELMs), which are composed of living matter …

Nanomedicine‐Enabled Sonomechanical, Sonopiezoelectric, Sonodynamic, and Sonothermal Therapy

X Song, Q Zhang, M Chang, L Ding… - Advanced …, 2023 - Wiley Online Library
Nanomedicine‐enabled/augmented ultrasound (US) medicine is a unique area of
interdisciplinary research that focuses on designing and engineering functional …

In-vivo programmable acoustic manipulation of genetically engineered bacteria

Y Yang, Y Yang, D Liu, Y Wang, M Lu, Q Zhang… - Nature …, 2023 - nature.com
Acoustic tweezers can control target movement through the momentum interaction between
an acoustic wave and an object. This technology has advantages over optical tweezers for …

Ultrasound-controllable engineered bacteria for cancer immunotherapy

MH Abedi, MS Yao, DR Mittelstein, A Bar-Zion… - Nature …, 2022 - nature.com
Rapid advances in synthetic biology are driving the development of genetically engineered
microbes as therapeutic agents for a multitude of human diseases, including cancer. The …

Ultrasound technology and biomaterials for precise drug therapy

Z Zhao, Q Saiding, Z Cai, M Cai, W Cui - Materials Today, 2023 - Elsevier
Advanced ultrasound technology and functional biomaterials can be used to achieve
precision drug therapy in different aspects such as dose, space, and/or time. At present …

Ultrasound-mediated blood–brain barrier opening: An effective drug delivery system for theranostics of brain diseases

J Wang, Z Li, M Pan, M Fiaz, Y Hao, Y Yan… - Advanced Drug Delivery …, 2022 - Elsevier
Blood-brain barrier (BBB) remains a significant obstacle to drug therapy for brain diseases.
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …

Bubble energy generator

X Yan, W Xu, Y Deng, C Zhang, H Zheng, S Yang… - Science …, 2022 - science.org
Bubbles have been extensively explored as energy carriers ranging from boiling heat
transfer and targeted cancer diagnosis. Yet, despite notable progress, the kinetic energy …

MOF‐Derived Nanoparticles with Enhanced Acoustical Performance for Efficient Mechano‐Sonodynamic Therapy

X Pan, Z Huang, J Guo, Q Wu, C Wang… - Advanced …, 2024 - Wiley Online Library
Ultrasound (US) generates toxic reactive oxygen species (ROS) by acting on
sonosensitizers for cancer treatment, and the mechanical damage induced by cavitation …

Magnetic–acoustic sequentially actuated CAR T cell microrobots for precision navigation and in situ antitumor immunoactivation

X Tang, Y Yang, M Zheng, T Yin, G Huang… - Advanced …, 2023 - Wiley Online Library
Despite its clinical success, chimeric antigen receptor T (CAR T)‐cell immunotherapy
remains limited in solid tumors, owing to the harsh physical barriers and …