Revisiting neoadjuvant therapy in non-small-cell lung cancer

SPL Saw, BH Ong, KLM Chua, A Takano… - The Lancet …, 2021 - thelancet.com
Despite the rapidly evolving treatment landscape in advanced non-small-cell lung cancer
(NSCLC), developments in neoadjuvant and adjuvant treatments have been nascent by …

The emerging role of stereotactic ablative radiotherapy for primary renal cell carcinoma: a systematic review and meta-analysis

RJM Correa, AV Louie, NG Zaorsky, EJ Lehrer… - European urology …, 2019 - Elsevier
Context Stereotactic ablative radiotherapy (SABR) is an emerging treatment option for
primary renal cell carcinoma (RCC). Objective To systematically review the literature on …

Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified …

JY Chang, RJ Mehran, L Feng, V Verma, Z Liao… - The Lancet …, 2021 - thelancet.com
Background A previous pooled analysis of the STARS and ROSEL trials showed higher
survival after stereotactic ablative radiotherapy (SABR) than with surgery for operable early …

Neoadjuvant durvalumab with or without stereotactic body radiotherapy in patients with early-stage non-small-cell lung cancer: a single-centre, randomised phase 2 …

NK Altorki, TE McGraw, AC Borczuk, A Saxena… - The Lancet …, 2021 - thelancet.com
Background Previous phase 2 trials of neoadjuvant anti-PD-1 or anti-PD-L1 monotherapy in
patients with early-stage non-small-cell lung cancer have reported major pathological …

Definitive radiotherapy in lieu of systemic therapy for oligometastatic renal cell carcinoma: a single-arm, single-centre, feasibility, phase 2 trial

C Tang, P Msaouel, K Hara, H Choi, V Le… - The lancet …, 2021 - thelancet.com
Background The role of radiotherapy in metastatic renal cell carcinoma is controversial. We
prospectively tested the feasibility and efficacy of radiotherapy to defer systemic therapy for …

Co-delivery of curcumin and paclitaxel by “core-shell” targeting amphiphilic copolymer to reverse resistance in the treatment of ovarian cancer

MD Zhao, JQ Li, FY Chen, W Dong… - International journal …, 2019 - Taylor & Francis
Background Ovarian cancer is a common malignancy in the female reproductive system with
a high mortality rate. The most important reason is multidrug resistance (MDR) of cancer …

Neoadjuvant immunotherapy for high-risk, resectable malignancies: scientific rationale and clinical challenges

M Krishnamoorthy, JG Lenehan… - JNCI: Journal of the …, 2021 - academic.oup.com
Neoadjuvant immunotherapy involves administering immune checkpoint inhibitors before
surgical resection in high-risk resectable disease. This strategy was shown to have a high …

Stereotactic MR-guided adaptive radiation therapy for peripheral lung tumors

T Finazzi, MA Palacios, CJA Haasbeek… - Radiotherapy and …, 2020 - Elsevier
Background and purpose We studied the benefits of using stereotactic MR-guided adaptive
radiation therapy (SMART) for delivery of SABR in peripherally located lung tumors …

[HTML][HTML] Squamous cell lung cancer

BR Sabbula, DP Gasalberti, SKR Mukkamalla… - StatPearls …, 2024 - ncbi.nlm.nih.gov
Objectives: Identify the etiology of squamous cell lung cancer. Assess the appropriate
history, physical, and evaluation of squamous cell lung cancer. Evaluate the management …

[HTML][HTML] A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation—part 4: systematic review of …

HS Park, FC Detterbeck, DC Madoff… - Journal of Thoracic …, 2022 - ncbi.nlm.nih.gov
Background Clinical decision-making for patients with stage I lung cancer is complex. It
involves multiple options [lobectomy, segmentectomy, wedge, stereotactic body …