Background and aims Advancing age is the most important risk factor of atrial fibrillation
(AF). The shortening of telomere length is a biomarker of biologic aging. There is an …

Disease overview Chronic neutrophilic leukemia (CNL) is a rare, often aggressive
myeloproliferative neoplasm (MPN) defined by persistent mature neutrophilic leukocytosis …

Abstract Disease Overview Chronic neutrophilic leukemia (CNL) is a rare, often aggressive
myeloproliferative neoplasm (MPN) defined by persistent mature neutrophilic leukocytosis …

The BTK inhibitors ibrutinib and acalabrutinib are FDA-approved drugs for the treatment of B
cell malignances. Both drugs have demonstrated clinical efficacy and safety profiles superior …

Acute physiology and chronic health evaluation II (APACHE-II) scoring system is used to
classify disease severity of patients in the intensive care unit. However, several limitations …

Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 2
(TIE2), the receptor for angiopoietins, has been found highly expressed in cervical cancer …

Pulmonary alveolar microlithiasis is an autosomal recessive lung disease caused by a
deficiency in the pulmonary epithelial Npt2b sodium-phosphate co-transporter that results in …

Pancreatic cancer (PC) is a fatal malignancy, threatening human health in worldwide. Long
non-coding RNAs (lncRNAs) have been acknowledged to be essential regulators in various …

The treatment of older, unfit patients with acute myeloid leukemia (AML) is challenging.
Based on preclinical data of Bruton tyrosine kinase expression/phosphorylation and ibrutinib …

Background: Epidemiological studies have reported an inconsistent relationship between
dietary inflammatory index (DII) and upper aerodigestive tract (UADT) cancer risk. However …