Exploring the role of unnatural amino acids in antimicrobial peptides

R Oliva, M Chino, K Pane, V Pistorio, A De Santis… - Scientific reports, 2018 - nature.com
Cationic antimicrobial peptides (CAMPs) are a promising alternative to treat multidrug-
resistant bacteria, which have developed resistance to all the commonly used antimicrobial …

Structure and dynamics of cetyltrimethylammonium chloride-sodium dodecylsulfate (CTAC-SDS) catanionic vesicles: High-value nano-vehicles from low-cost …

IR Krauss, R Imperatore, A De Santis, A Luchini… - Journal of colloid and …, 2017 - Elsevier
Hypothesis Catanionic vesicles based on large-scale produced surfactants represent a
promising platform for the design of innovative, effective and relatively inexpensive nano …

Omega-3 fatty acids regulate the interaction of the Alzheimer's Aβ (25–35) peptide with lipid membranes

G Vitiello, S Di Marino, AM D'Ursi, G D'Errico - Langmuir, 2013 - ACS Publications
Polyunsaturated omega-3 fatty acids are increasingly proposed as dietary supplements able
to reduce the risk of development or progression of the Alzheimer's disease (AD). To date …

A new design for nucleolipid-based Ru (III) complexes as anticancer agents

D Montesarchio, G Mangiapia, G Vitiello… - Dalton …, 2013 - pubs.rsc.org
In continuation with our studies concerning the synthesis, characterization and biological
evaluation of nucleolipidic Ru (III) complexes, a novel design for this family of potential …

Enhancement of the uptake and cytotoxic activity of doxorubicin in cancer cells by novel cRGD-semipeptide-anchoring liposomes

L Battistini, P Burreddu, A Sartori, D Arosio… - Molecular …, 2014 - ACS Publications
Novel liposemipeptides hanging cyclic azabicycloalkane-RGD or aminoproline-RGD
terminals were synthesized and incorporated into liposomal nanoparticles cAba/cAmpRGD …

Versatile cyclodextrin nanotube synthesis with functional anchors for efficient ion channel formation: design, characterization and ion conductance

H Mamad-Hemouch, L Bacri, C Huin, C Przybylski… - Nanoscale, 2018 - pubs.rsc.org
Biomimetic ion channels with different materials have been extensively designed to study
the dynamics in a confined medium. These channels allow the development of several …

[HTML][HTML] On the microscopic and mesoscopic perturbations of lipid bilayers upon interaction with the MPER domain of the HIV glycoprotein gp41

R Oliva, A Emendato, G Vitiello, A De Santis… - … et Biophysica Acta (BBA …, 2016 - Elsevier
The effect of the 665-683 fragment of the HIV fusion glycoprotein 41, corresponding to the
MPER domain of the protein and named gp41MPER, on the microscopic structure and …

[HTML][HTML] Calixarene-based artificial ionophores for chloride transport across natural liposomal bilayer: Synthesis, structure-function relationships, and computational …

S Pilato, M Aschi, M Bazzoni, FC Bonati, G Cera… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract An amphiphilic calix [6] arene, alone or complexed with an axle to form a pseudo-
rotaxane, has been embedded into liposomes prepared from 1-palmitoyl-2-oleoyl-sn …

[HTML][HTML] Ionophores at work: Exploring the interaction of guanosine-based amphiphiles with phospholipid membranes

G Vitiello, D Musumeci, A Koutsioubas… - … et Biophysica Acta (BBA …, 2017 - Elsevier
An amphiphilic derivative of guanosine, carrying a myristoyl group at the 5′-position and
two methoxy (triethylene glycol) appendages at the 2′ and 3′-positions (1), endowed with …

Guanine-based amphiphiles: synthesis, ion transport properties and biological activity

D Musumeci, C Irace, R Santamaria, D Milano… - Bioorganic & Medicinal …, 2015 - Elsevier
Novel amphiphilic guanine derivatives, here named Gua1 and Gua2, have been prepared
through few, simple and efficient synthetic steps. In ion transport experiments through …