Bipolar disorders
Bipolar disorders are a complex group of severe and chronic disorders that includes bipolar
I disorder, defined by the presence of a syndromal, manic episode, and bipolar II disorder …
I disorder, defined by the presence of a syndromal, manic episode, and bipolar II disorder …
The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness
Background The poor physical health of people with mental illness is a multifaceted,
transdiagnostic, and global problem. People with mental illness have an increased risk of …
transdiagnostic, and global problem. People with mental illness have an increased risk of …
Incidence, prevalence, and global burden of schizophrenia-data, with critical appraisal, from the Global Burden of Disease (GBD) 2019
Schizophrenia substantially contributes to the burden of mental disorders. Schizophrenia's
burden and epidemiological estimates in some countries have been published, but updated …
burden and epidemiological estimates in some countries have been published, but updated …
Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with …
Background Antipsychotic treatment is associated with metabolic disturbance. However, the
degree to which metabolic alterations occur in treatment with different antipsychotics is …
degree to which metabolic alterations occur in treatment with different antipsychotics is …
Cardiovascular disease in patients with severe mental illness
Individuals diagnosed with schizophrenia or bipolar disorder have a life expectancy 15–20
years shorter than that in the general population. The rate of unnatural deaths, such as …
years shorter than that in the general population. The rate of unnatural deaths, such as …
The clinical characterization of the patient with primary psychosis aimed at personalization of management
The current management of patients with primary psychosis worldwide is often remarkably
stereotyped. In almost all cases an antipsychotic medication is prescribed, with second …
stereotyped. In almost all cases an antipsychotic medication is prescribed, with second …
[HTML][HTML] Half a century of research on antipsychotics and schizophrenia: A scientometric study of hotspots, nodes, bursts, and trends
Abstract Changes over 50 years of research on antipsychotics in schizophrenia have
occurred. A scientometric synthesis of such changes over time and a measure of …
occurred. A scientometric synthesis of such changes over time and a measure of …
Short‐chain fatty acids: microbial metabolites that alleviate stress‐induced brain–gut axis alterations
Key points Chronic (psychosocial) stress changes gut microbiota composition, as well as
inducing behavioural and physiological deficits. The microbial metabolites short‐chain fatty …
inducing behavioural and physiological deficits. The microbial metabolites short‐chain fatty …
20‐year follow‐up study of physical morbidity and mortality in relationship to antipsychotic treatment in a nationwide cohort of 62,250 patients with schizophrenia …
H Taipale, A Tanskanen, J Mehtälä… - World …, 2020 - Wiley Online Library
Antipsychotics are effective in preventing relapses of schizophrenia, but it is generally
believed that their long‐term use is harmful for patients' physical well‐being. However, there …
believed that their long‐term use is harmful for patients' physical well‐being. However, there …
Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large‐scale meta‐analysis of 3,211,768 …
People with severe mental illness (SMI)–schizophrenia, bipolar disorder and major
depressive disorder–appear at risk for cardiovascular disease (CVD), but a comprehensive …
depressive disorder–appear at risk for cardiovascular disease (CVD), but a comprehensive …