Environmental risk factors for multiple sclerosis: a review with a focus on molecular mechanisms
Multiple sclerosis (MS) is a chronic disabling disease of the central nervous system
commonly affecting young adults. Pathologically, there are patches of inflammation …
commonly affecting young adults. Pathologically, there are patches of inflammation …
Worldwide prevalence of familial multiple sclerosis: A systematic review and meta-analysis
Background Several studies have suggested that the existence of a history of multiple
sclerosis (MS) in family, is one of the predisposing factors for MS. Based on our knowledge …
sclerosis (MS) in family, is one of the predisposing factors for MS. Based on our knowledge …
Modest familial risks for multiple sclerosis: a registry-based study of the population of Sweden
Data on familial recurrence rates of complex diseases such as multiple sclerosis give
important hints to aetiological factors such as the importance of genes and environment. By …
important hints to aetiological factors such as the importance of genes and environment. By …
Modelling genetic susceptibility to multiple sclerosis with family data
A genetic contribution to susceptibility is well established in multiple sclerosis (MS) and 57
associated genetic loci have been identified. We have undertaken a meta-analysis of …
associated genetic loci have been identified. We have undertaken a meta-analysis of …
[HTML][HTML] Prevalence of multiple sclerosis in the middle black sea region of Turkey and demographic characteristics of patients
N Akdemir, M Terzi, N Arslan… - Archives of …, 2017 - ncbi.nlm.nih.gov
Methods Patients living in the Middle Black Sea Region and who were diagnosed with MS
were included. The study was designed based hospital of Turkey. Results A total of 1,787 …
were included. The study was designed based hospital of Turkey. Results A total of 1,787 …
Increasing prevalence of familial recurrence of multiple sclerosis in Iran: a population based study of Tehran registry 1999–2015
Background Tehran is the capital of Iran with an increasing multiple sclerosis (MS)
prevalence. A retrospective population-based study was conducted to evaluate the trends of …
prevalence. A retrospective population-based study was conducted to evaluate the trends of …
The CombiRx trial of combined therapy with interferon and glatiramer acetate in relapsing remitting MS: Design and baseline characteristics
Background Interferon-β1a (IFNB) and glatiramer acetate (GA) are distinct therapies which
are both partially effective for relapsing MS. It is not known if combining the two treatments …
are both partially effective for relapsing MS. It is not known if combining the two treatments …
Epidemiology of familial multiple sclerosis: A population-based study in Tehran during 1999–2018
Background Familial multiple sclerosis (FMS) studies are valuable as they reveal the effects
of environment and genes on the etiology of the disease. Objective The present study was …
of environment and genes on the etiology of the disease. Objective The present study was …
The major cause of multiple sclerosis is environmental: genetics has a minor role-yes
BV Taylor - Multiple Sclerosis Journal, 2011 - journals.sagepub.com
(CNS) demyelination. 10 Adjusting for the frequency of the most powerful genetic
association HLA DRB1* 15: 01 does not have a significant influence on the gradient in …
association HLA DRB1* 15: 01 does not have a significant influence on the gradient in …
Familial forms of multiple sclerosis and neuromyelitis optica at an MS center in Rio de Janeiro State, Brazil
RM Papais-Alvarenga, FFCC Pereira… - Journal of the …, 2015 - Elsevier
Objective To describe familial forms of demyelinating diseases from an MS referral center in
Río de Janeiro State, Brazil. Methods A descriptive, cross-sectional study was done to …
Río de Janeiro State, Brazil. Methods A descriptive, cross-sectional study was done to …