Application of targeted mass spectrometry in bottom-up proteomics for systems biology research
The enormous diversity of proteoforms produces tremendous complexity within cellular
proteomes, facilitates intricate networks of molecular interactions, and constitutes a …
proteomes, facilitates intricate networks of molecular interactions, and constitutes a …
Current trends in quantitative proteomics–an update
Proteins can provide insights into biological processes at the functional level, so they are
very promising biomarker candidates. The quantification of proteins in biological samples …
very promising biomarker candidates. The quantification of proteins in biological samples …
Proteomic signature of extracellular vesicles for lung cancer recognition
SE Novikova, NA Soloveva, TE Farafonova… - Molecules, 2021 - mdpi.com
The proteins of extracellular vesicles (EVs) that originate from tumors reflect the producer
cells' proteomes and can be detected in biological fluids. Thus, EVs provide proteomic …
cells' proteomes and can be detected in biological fluids. Thus, EVs provide proteomic …
[HTML][HTML] The effects of spaceflight factors on the human plasma proteome, including both real space missions and ground-based experiments
AG Brzhozovskiy, AS Kononikhin… - International Journal of …, 2019 - mdpi.com
The aim of the study was to compare proteomic data on the effects of spaceflight factors on
the human body, including both real space missions and ground-based experiments. LC …
the human body, including both real space missions and ground-based experiments. LC …
[HTML][HTML] Evaluation of haptoglobin and its proteoforms as glioblastoma markers
Haptoglobin (Hp) is a blood plasma glycoprotein that plays a critical role in tissue protection
and the prevention of oxidative damage. Haptoglobin is an acute-phase protein, its …
and the prevention of oxidative damage. Haptoglobin is an acute-phase protein, its …
Number of detected proteins as the function of the sensitivity of proteomic technology in human liver cells
Aims: The main goal of the Russian part of C-HPP is to detect and functionally annotate
missing proteins (PE2-PE4) encoded by human chromosome 18. To achieve this goal, it is …
missing proteins (PE2-PE4) encoded by human chromosome 18. To achieve this goal, it is …
200+ protein concentrations in healthy human blood plasma: Targeted quantitative SRM SIS screening of chromosomes 18, 13, Y, and the mitochondrial chromosome …
This work continues the series of the quantitative measurements of the proteins encoded by
different chromosomes in the blood plasma of a healthy person. Selected Reaction …
different chromosomes in the blood plasma of a healthy person. Selected Reaction …
Determining plasma protein variation parameters as a prerequisite for biomarker studies—a TMT-based LC-MSMS proteome investigation
Specific plasma proteins serve as valuable markers for various diseases and are in many
cases routinely measured in clinical laboratories by fully automated systems. For safe …
cases routinely measured in clinical laboratories by fully automated systems. For safe …
Spaceflight induced changes in the human proteome
AS Kononikhin, NL Starodubtseva… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Spaceflight is one of the most extreme conditions encountered by humans:
Individuals are exposed to radiation, microgravity, hypodynamia, and will experience …
Individuals are exposed to radiation, microgravity, hypodynamia, and will experience …
State of the Art of chromosome 18-centric HPP in 2016: Transcriptome and proteome profiling of liver tissue and HepG2 cells
EV Poverennaya, AT Kopylov… - Journal of Proteome …, 2016 - ACS Publications
A gene-centric approach was applied for a large-scale study of expression products of a
single chromosome. Transcriptome profiling of liver tissue and HepG2 cell line was …
single chromosome. Transcriptome profiling of liver tissue and HepG2 cell line was …