Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021 - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

The living interface between synthetic biology and biomaterial design

AP Liu, EA Appel, PD Ashby, BM Baker, E Franco… - Nature materials, 2022 - nature.com
Recent far-reaching advances in synthetic biology have yielded exciting tools for the
creation of new materials. Conversely, advances in the fundamental understanding of soft …

Peptide design and self-assembly into targeted nanostructure and functional materials

NJ Sinha, MG Langenstein, DJ Pochan… - Chemical …, 2021 - ACS Publications
Peptides have been extensively utilized to construct nanomaterials that display targeted
structure through hierarchical assembly. The self-assembly of both rationally designed …

Soft bioelectronics based on nanomaterials

KW Cho, SH Sunwoo, YJ Hong, JH Koo… - Chemical …, 2021 - ACS Publications
Recent advances in nanostructured materials and unconventional device designs have
transformed the bioelectronics from a rigid and bulky form into a soft and ultrathin form and …

Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact

Y Gao, K Peng, S Mitragotri - Advanced Materials, 2021 - Wiley Online Library
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …

Cell spheroid creation by transcytotic intercellular gelation

J Guo, F Wang, Y Huang, H He, W Tan, M Yi… - Nature …, 2023 - nature.com
Cell spheroids bridge the discontinuity between in vitro systems and in vivo animal models.
However, inducing cell spheroids by nanomaterials remains an inefficient and poorly …

Design of mechanical-robust phosphorescence materials through covalent click reaction

R Tian, S Gao, K Li, C Lu - Nature Communications, 2023 - nature.com
It remains a great challenge to engineer materials with strong and stable interactions for the
simultaneously mechanical-robust and room temperature phosphorescence-efficient …

Fabrication of bioinspired hydrogels: challenges and opportunities

H Fan, JP Gong - Macromolecules, 2020 - ACS Publications
Since the birth of synthetic hydrogel 60 years ago, hydrogels possessing various useful
properties and functions have been developed. The research directions of hydrogels have …

Protein-directed, hydrogen-bonded biohybrid framework

G Chen, S Huang, Y Shen, X Kou, X Ma, S Huang… - Chem, 2021 - cell.com
Here, we describe a versatile protein-directed assembly strategy that enables the
organization of different types of proteins and organic linkers into a highly crystalline hybrid …

Intranuclear nanoribbons for selective killing of osteosarcoma cells

S Liu, Q Zhang, H He, M Yi, W Tan… - Angewandte Chemie …, 2022 - Wiley Online Library
Herein, we show intranuclear nanoribbons formed upon dephosphorylation of leucine‐rich L‐
or D‐phosphopeptide catalyzed by alkaline phosphatase (ALP) to selectively kill …