Key changes to the World Health Organization (WHO) classification of female genital tumours introduced in the 5th edition (2020)

WG McCluggage, N Singh, CB Gilks - Histopathology, 2022 - Wiley Online Library
An updated World Health Organization (WHO) classification of female genital tumours was
published in autumn 2020. We discuss the major new additions to and changes from the …

Rethinking ovarian cancer: recommendations for improving outcomes

S Vaughan, JI Coward, RC Bast Jr, A Berchuck… - Nature Reviews …, 2011 - nature.com
There have been major advances in our understanding of the cellular and molecular biology
of the human malignancies that are collectively referred to as ovarian cancer. At a recent …

Ovarian cancer statistics, 2018

LA Torre, B Trabert, CE DeSantis… - CA: a cancer journal …, 2018 - Wiley Online Library
In 2018, there will be approximately 22,240 new cases of ovarian cancer diagnosed and
14,070 ovarian cancer deaths in the United States. Herein, the American Cancer Society …

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins

G Lu, RE Middleton, H Sun, MV Naniong, CJ Ott… - Science, 2014 - science.org
Thalidomide-like drugs such as lenalidomide are clinically important treatments for multiple
myeloma and show promise for other B cell malignancies. The biochemical mechanisms …

The disparate origins of ovarian cancers: pathogenesis and prevention strategies

AN Karnezis, KR Cho, CB Gilks, CL Pearce… - Nature Reviews …, 2017 - nature.com
Ovarian cancer is the fifth cause of cancer-related death in women and comprises a
histologically and genetically broad range of tumours, including those of epithelial, sex cord …

ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas

KC Wiegand, SP Shah, OM Al-Agha… - … England Journal of …, 2010 - Mass Medical Soc
Background Ovarian clear-cell and endometrioid carcinomas may arise from endometriosis,
but the molecular events involved in this transformation have not been described. Methods …

[HTML][HTML] International network of cancer genome projects

International Cancer Genome Consortium - Nature, 2010 - ncbi.nlm.nih.gov
Abstract The International Cancer Genome Consortium (ICGC) was launched to coordinate
large-scale cancer genome studies in tumors from 50 different cancer types and/or subtypes …

Single-molecule sequencing and optical map** yields an improved genome of woodland strawberry (Fragaria vesca) with chromosome-scale contiguity

PP Edger, R VanBuren, M Colle, TJ Poorten… - …, 2018 - academic.oup.com
Background Although draft genomes are available for most agronomically important plant
species, the majority are incomplete, highly fragmented, and often riddled with assembly …

Advances in understanding cancer genomes through second-generation sequencing

M Meyerson, S Gabriel, G Getz - Nature Reviews Genetics, 2010 - nature.com
Cancers are caused by the accumulation of genomic alterations. Therefore, analyses of
cancer genome sequences and structures provide insights for understanding cancer …

SomaticSniper: identification of somatic point mutations in whole genome sequencing data

DE Larson, CC Harris, K Chen, DC Koboldt… - …, 2012 - academic.oup.com
Motivation: The sequencing of tumors and their matched normals is frequently used to study
the genetic composition of cancer. Despite this fact, there remains a dearth of available …