Antimutagenic compounds and their possible mechanisms of action

K Słoczyńska, B Powroźnik, E Pękala… - Journal of applied …, 2014 - Springer
Mutagenicity refers to the induction of permanent changes in the DNA sequence of an
organism, which may result in a heritable change in the characteristics of living systems …

Characterization of gamma-ray and neutron radiation absorption properties of synthesized quinoline derivatives and their genotoxic potential

B Alaylar, B Aygün, K Turhan, G Karadayi… - Radiation physics and …, 2021 - Elsevier
In this study, six different types of quinoline derivatives were synthesized, which can be used
as an anti-radiation drug for active matter and its effects against radiation was determined …

[PDF][PDF] Fruits and vegetables as dietary sources of antimutagens

S Gautam, S Saxena, S Kumar - J Food Chem …, 2016 - foodchemistryjournal.com
Mutation is the process leading to heritable changes in the genetic material of an organism
and caused mainly by the external factors, including chemical and physical agents, or can …

Determination of toxicity and radioprotective properties of bacterial and fungal eumelanin pigments

S Bayram, B Aygün, M Karadayi, B Alaylar… - … Journal of Radiation …, 2023 - Taylor & Francis
Purpose Determination of the protective property of melanin, an organic polymer class
consisting of phenolic and/or indolic compounds isolated from bacteria and fungi, against …

Phytochemical Analysis and Evaluation of Genotoxic, Antigenotoxic Effects in Bacterial Models, and Hypoglycemic Activity of Epilobium angustifolium L. with …

H Yuca, M Karadayı, S Karakaya, A Civaş… - Chemistry & …, 2023 - Wiley Online Library
This study examined the effects of methanol extract and its sub‐extracts from Epilobium
angustifolium on α‐glucosidase and α‐amylase activity. Secondary metabolites and amino …

Evaluation of the protective properties and genotoxic potential of pyrazolo pyridine derivatives against neutron and gamma radiation using the Ames/Salmonella test …

B Aygün, B Alaylar, K Turhan, M Karadayı… - … Journal of Radiation …, 2024 - Taylor & Francis
Purpose Nuclear applications are being increasingly used in various fields, necessitating
studies to protect from radiation hazards and their effects. In this study, five different chemical …

In Vitro Genotoxic and Antigenotoxic Effects of Ten Novel Synthesized 4‐Thiazolidinone Derivatives

B Alaylar, M Güllüce, K Turhan, TY Koç… - Chemistry & …, 2023 - Wiley Online Library
Heterocyclic compounds are found in a variety of drug molecules, and bioactive natural
products. 4‐Thiazolidinones (4‐TZDs), which represent an important class of heterocyclic …

Metal-free nitroxyl radical-mediated β-C (sp 3)–H amination of saturated ketones with heteroaryl halides: multiple roles of TEMPO

P Qian, Y Deng, H Mei, J Han, Y Pan - Chemical Communications, 2017 - pubs.rsc.org
The first metal-free nitroxyl-radical-mediated β-amination of saturated ketones by using
heteroaryl halides as amide precursors has been developed. This reaction proceeds …

Ultrasonic synthesis, characterization of β-aminoketones by bismuth (III) triflate and determination of antigenotoxic properties

SA Ozturkcan, K Turhan, Z Turgut… - Toxicology and …, 2015 - journals.sagepub.com
Direct-type catalytic Mannich reaction for the synthesis of β-aminoketones from
cyclohexanone, substituted aromatic amines and aromatic or hetero-aromatic aldehydes …

Current trends and future perspectives of antimutagenic agents

AM AbdelHakem, ESMN Abdelhafez… - … and Test Methods, 2020 - books.google.com
Mutation is the process leading to heritable changes in DNA caused mainly by internal and
external factors. Recently, studies on mutagenic agents have been increased due to …