Fluorescent probes for targeting the Golgi apparatus: design strategies and applications

S Xu, KC Yan, ZH Xu, Y Wang, TD James - Chemical Society Reviews, 2024 - pubs.rsc.org
The Golgi apparatus is an essential organelle constructed by the stacking of flattened
vesicles, that is widely distributed in eukaryotic cells and is dynamically regulated during cell …

The design and bioimaging applications of NIR fluorescent organic dyes with high brightness

J Wu, Z Shi, L Zhu, J Li, X Han, M Xu… - Advanced Optical …, 2022 - Wiley Online Library
Due to the merits of decreased photon attenuation, autofluorescence, and scattering, the
near‐infrared (NIR, 700–1700 nm) region is an important window in the field of biomedicine …

Method to diversify cyanine chromophore functionality enables improved biomolecule tracking and intracellular imaging

SM Usama, SC Marker, DH Li… - Journal of the …, 2023 - ACS Publications
Heptamethine indocyanines are invaluable probes for near-infrared (NIR) imaging. Despite
broad use, there are only a few synthetic methods to assemble these molecules, and each …

Doubly Strapped Zwitterionic NIR‐I and NIR‐II Heptamethine Cyanine Dyes for Bioconjugation and Fluorescence Imaging

DH Li, RS Gamage, AG Oliver, NL Patel… - Angewandte …, 2023 - Wiley Online Library
Heptamethine cyanine dyes enable deep tissue fluorescence imaging in the near infrared
(NIR) window. Small molecule conjugates of the benchmark dye ZW800‐1 have been tested …

Molecular imaging nanoprobes for theranostic applications

H He, X Zhang, L Du, M Ye, Y Lu, J Xue, J Wu… - Advanced Drug Delivery …, 2022 - Elsevier
As a non-invasive imaging monitoring method, molecular imaging can provide the location
and expression level of disease signature biomolecules in vivo, leading to early diagnosis of …

Tris‐benzo[cd]indole Cyanine Enables the NIR‐photosensitized Radical and Thiol‐ene Polymerizations at 940 nm

C Elian, B Mourot, C Benbouziyane… - Angewandte Chemie …, 2023 - Wiley Online Library
A near‐infrared‐absorbing heptamethine (HM+) incorporating three bulky benzo [cd] indole
heterocycles was designed to efficiently prevent self‐aggregation of the dye, which results in …

A “crossbreeding” dyad strategy for bright and small-molecular weight near-infrared fluorogens: From the structural design to boost aggregation-induced emission

J Li, M Zhao, J Huang, P Liu, X Luo, Y Zhang… - Coordination Chemistry …, 2022 - Elsevier
The development of high-performance near-infrared fluorophores has gained tremendous
attention for spatiotemporally in vivo dynamical bioimaging. The proposed π-conjugated …

NIR‐II cyanine@ albumin fluorophore for deep tissue imaging and imaging‐guided surgery

Y Zhang, Y Jia, S Zhu - SmartMat, 2024 - Wiley Online Library
Abstract The near‐infrared (NIR)‐II bioimaging technique is highly important for both
diagnosing and treating life‐threatening diseases due to its exceptional imaging …

Tumor‐Targeting Near‐Infrared Dimeric Heptamethine Cyanine Photosensitizers with an Aromatic Diphenol Linker for Imaging‐Guided Cancer Phototherapy

Y Xu, J Yu, J Hu, K Sun, W Lu, F Zeng… - Advanced …, 2023 - Wiley Online Library
Phototherapy is considered a promising alternative to conventional tumor treatments due to
its noninvasive modality and effective therapeutic effect. However, designing a …

A Selenium‐Substituted Heptamethine Cyanine Photosensitizer for Near‐Infrared Photodynamic Therapy

J Sun, E Feng, Y Shao, F Lv, Y Wu, J Tian… - …, 2022 - Wiley Online Library
Photodynamic therapy (PDT) is a relatively safe approach to cancer treatment without
significant systemic side effects or drug resistance. However, the current PDT efficiency is …