Nitrosative stress in Parkinson's disease
MG Stykel, SD Ryan - npj Parkinson's Disease, 2022 - nature.com
Parkinson's Disease (PD) is a neurodegenerative disorder characterized, in part, by the loss
of dopaminergic neurons within the nigral-striatal pathway. Multiple lines of evidence …
of dopaminergic neurons within the nigral-striatal pathway. Multiple lines of evidence …
[HTML][HTML] The role of nitric oxide in brain disorders: Autism spectrum disorder and other psychiatric, neurological, and neurodegenerative disorders
Nitric oxide (NO) is a multifunctional signalling molecule and a neurotransmitter that plays
an important role in physiological and pathophysiological processes. In physiological …
an important role in physiological and pathophysiological processes. In physiological …
Mechanistic insight into female predominance in Alzheimer's disease based on aberrant protein S-nitrosylation of C3
Protein S-nitros (yl) ation (SNO) is a posttranslational modification involved in diverse
processes in health and disease and can contribute to synaptic damage in Alzheimer's …
processes in health and disease and can contribute to synaptic damage in Alzheimer's …
Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration
Neurodegenerative disorders like Alzheimer's disease and Parkinson's disease are
characterized by progressive degeneration of synapses and neurons. Accumulation of …
characterized by progressive degeneration of synapses and neurons. Accumulation of …
The contribution of an imbalanced redox signalling to neurological and neurodegenerative conditions
Nitric oxide and other redox active molecules such as oxygen free radicals provide essential
signalling in diverse neuronal functions, but their excess production and insufficient …
signalling in diverse neuronal functions, but their excess production and insufficient …
Tetrandrine ameliorates cognitive deficits and mitigates tau aggregation in cell and animal models of tauopathies
Background Tauopathies are neurodegenerative diseases that are associated with the
pathological accumulation of tau-containing tangles in the brain. Tauopathy can impair …
pathological accumulation of tau-containing tangles in the brain. Tauopathy can impair …
RNF213 and GUCY1A3 in moyamoya disease: key regulators of metabolism, inflammation, and vascular stability
Y Mineharu, S Miyamoto - Frontiers in Neurology, 2021 - frontiersin.org
Moyamoya disease is an idiopathic chronically progressive cerebrovascular disease, which
causes both ischemic and hemorrhagic stroke. Genetic studies identified RNF213/Mysterin …
causes both ischemic and hemorrhagic stroke. Genetic studies identified RNF213/Mysterin …
Proteomics of autism and Alzheimer's mouse models reveal common alterations in mTOR signaling pathway
S Mencer, M Kartawy, F Lendenfeld, H Soluh… - Translational …, 2021 - nature.com
Autism spectrum disorder (ASD) and Alzheimer's disease (AD) are two different neurological
disorders that share common clinical features, such as language impairment, executive …
disorders that share common clinical features, such as language impairment, executive …
An inventory of crosstalk between ubiquitination and other post-translational modifications in orchestrating cellular processes
H Barbour, NS Nkwe, B Estavoyer, C Messmer… - IScience, 2023 - cell.com
Ubiquitination is an important post-translational modification (PTM) that regulates a large
spectrum of cellular processes in eukaryotes. Abnormalities in ubiquitin signaling underlie …
spectrum of cellular processes in eukaryotes. Abnormalities in ubiquitin signaling underlie …
Arsenic alters nitric oxide signaling similar to autism spectrum disorder and Alzheimer's disease-associated mutations
Epidemiological studies have proven that exposure to Arsenic (AS) leads to the
development of many neurological disorders. However, few studies have investigated its …
development of many neurological disorders. However, few studies have investigated its …