Stealth and pseudo-stealth nanocarriers

P Wen, W Ke, A Dirisala, K Toh, M Tanaka… - Advanced drug delivery …, 2023 - Elsevier
The stealth effect plays a central role on capacitating nanomaterials for drug delivery
applications through improving the pharmacokinetics such as blood circulation …

Gold complexes in anticancer therapy: From new design principles to particle‐based delivery systems

G Moreno‐Alcántar, P Picchetti… - Angewandte Chemie …, 2023 - Wiley Online Library
The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …

Lipid droplet-targeting near-infrared carbon dots with high-specificity dual-report function for diagnosing hepatocellular carcinoma and evaluating its …

J Wang, Y Sun, J Hu, Y Guo, L Qu, Z Li - Chemical Engineering Journal, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is a metabolic disease with high mortality caused by
abnormal deposition of lipid droplets (LDs). The number and distribution of LDs can …

Toxicological impact of titanium dioxide nanoparticles and food-grade titanium dioxide (E171) on human and environmental health

F Fiordaliso, P Bigini, M Salmona… - Environmental Science …, 2022 - pubs.rsc.org
The widespread use of titanium dioxide (TiO2) as a pigment, mostly in the form of
nanoparticles (NPs), for a variety of applications, arouses increasing concerns about its …

[HTML][HTML] Mesoporous silicas in materials engineering: Nanodevices for bionanotechnologies

E Mazzotta, M De Santo, D Lombardo, A Leggio… - Materials Today Bio, 2022 - Elsevier
In this review, the most valuable opportunities offered by mesoporous silica nanoparticles in
the field of development of nanodevices for bionanotechnology applications are reviewed …

Biomineralization of DNA nanoframeworks for intracellular delivery, on-demand diagnosis, and synergistic cancer treatments

X Wang, X Shen, J Li, X Ge, J Ouyang… - Analytical Chemistry, 2022 - ACS Publications
DNA nanoframeworks, with great biological information and controlled framework structures,
exhibit great potentials in biological applications. Their applications are normally limited by …

Remodeling the hepatic fibrotic microenvironment with emerging nanotherapeutics: a comprehensive review

X Zhao, FK Amevor, X Xue, C Wang, Z Cui… - Journal of …, 2023 - Springer
Liver fibrosis could be the last hope for treating liver cancer and remodeling of the hepatic
microenvironment has emerged as a strategy to promote the ablation of liver fibrosis. In …

Enhancing Pt (IV) complexes' anticancer activity upon encapsulation in stimuli‐responsive nanocages

M Sancho‐Albero, G Facchetti, N Panini… - Advanced …, 2023 - Wiley Online Library
Platinum‐based chemotherapy is the first‐line treatment for different cancer types, and in
particular, for malignant pleural mesothelioma patients (a tumor histotype with urgent …

Cargo-loaded lipid-shielded breakable organosilica nanocages for enhanced drug delivery

M Sancho-Albero, G Rosso, L De Cola, V Cauda - Nanoscale, 2023 - pubs.rsc.org
The recent nanomedicine advancements have introduced a variety of smart nanoparticles in
cancer treatment and diagnostics. However, their application to the clinic is still hindered by …

Supramolecular Nucleic Acid-Based Organosilica Nanoparticles Responsive to Physical and Biological Inputs

P Picchetti, S Volpi, M Sancho-Albero… - Journal of the …, 2023 - ACS Publications
Organosilica nanoparticles that contain responsive organic building blocks as constitutive
components of the silica network offer promising opportunities for the development of …