Artemisia annua L. is used throughout Asia and Africa as tea and press juice to treat malaria
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …

The side-effects and long-term sequelae of anti-cancer chemotherapy remain a major
source of concern for both patients and clinicians despite the improved efficacy and …

The field of Traditional Chinese Medicine (TCM) represents a vast and largely untapped
resource for modern medicine. Exemplified by the success of the antimalarial artemisinin …

In vivo ADME testing is costly, time-consuming, and puts animal lives at risk, whereas in
silico ADME testing is safer, simpler, and faster. This study will use in silico methodologies …

Artemisinins are sesquiterpene lactones with a peroxide moiety that are isolated from the
herb Artemisia annua. It has been used for centuries for the treatment of fever and chills, and …

Background Apoptosis and other forms of cell death have been intensively investigated in
the past years to explain the mode of action of synthetic anticancer drugs and natural …

Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …

Artemisinin is the crucial ingredient of artemisia annua, a traditional Chinese medicine used
for the therapy of malaria in China for hundreds of years. In recent years, the anticancer …

Artemisinin and its derivatives (collectively termed as artemisinins) are among the most
important and effective antimalarial drugs, with proven safety and efficacy in clinical use …

Despite international efforts to 'roll back malaria'the 2008 World Malaria Report revealed the
disease still affects approximately 3 billion people in 109 countries; 45 within the WHO …