Disease modeling using 3D organoids derived from human induced pluripotent stem cells

BX Ho, NMQ Pek, BS Soh - International journal of molecular sciences, 2018 - mdpi.com
The rising interest in human induced pluripotent stem cell (hiPSC)-derived organoid culture
has stemmed from the manipulation of various combinations of directed multi-lineage …

PC12 cell line: cell types, coating of culture vessels, differentiation and other culture conditions

B Wiatrak, A Kubis-Kubiak, A Piwowar, E Barg - Cells, 2020 - mdpi.com
The PC12 cell line is one of the most commonly used in neuroscience research, including
studies on neurotoxicity, neuroprotection, neurosecretion, neuroinflammation, and …

In Vitro Research Reproducibility: Kee** Up High Standards

C Hirsch, S Schildknecht - Frontiers in pharmacology, 2019 - frontiersin.org
Concern regarding the reproducibility of observations in life science research has emerged
in recent years, particularly in view of unfavorable experiences with preclinical in vivo …

The use of collagen-based scaffolds to simulate prostate cancer bone metastases with potential for evaluating delivery of nanoparticulate gene therapeutics

KA Fitzgerald, J Guo, EG Tierney, CM Curtin… - Biomaterials, 2015 - Elsevier
Prostate cancer bone metastases are a leading cause of cancer-related death in men with
current treatments offering only marginally improved rates of survival. Advances in the …

Lipid uptake is an androgen-enhanced lipid supply pathway associated with prostate cancer disease progression and bone metastasis

KD Tousignant, A Rockstroh, A Taherian Fard… - Molecular Cancer …, 2019 - AACR
De novo lipogenesis is a well-described androgen receptor (AR)–regulated metabolic
pathway that supports prostate cancer tumor growth by providing fuel, membrane material …

Prostate cancer cells of increasing metastatic potential exhibit diverse contractile forces, cell stiffness, and motility in a microenvironment stiffness-dependent manner

CW Molter, EF Muszynski, Y Tao, T Trivedi… - Frontiers in Cell and …, 2022 - frontiersin.org
During metastasis, all cancer types must migrate through crowded multicellular
environments. Simultaneously, cancers appear to change their biophysical properties …

[HTML][HTML] Potential anti-cancer properties of malvidin and its glycosides: Evidence from in vitro and in vivo studies

R Sood, HK Choi, HJ Lee - Journal of Functional Foods, 2024 - Elsevier
Malvidin and its glycosides have been studied for their anti-carcinogenic potential in various
forms of cancer, however the in-depth review for malvidin and its glycosides in in vitro and in …

PD-L1 influences cell spreading, migration and invasion in head and neck cancer cells

J Eichberger, D Schulz, K Pscheidl, M Fiedler… - International journal of …, 2020 - mdpi.com
The programmed cell death protein-1 (PD-1)/programmed cell death ligand-1 (PD-L1) axis
blockade has been implemented in advanced-stage tumor therapy for various entities …

Upgrading well plates using open microfluidic patterning

SB Berry, T Zhang, JH Day, X Su, IZ Wilson, E Berthier… - Lab on a Chip, 2017 - pubs.rsc.org
Cellular communication between multiple cell types is a ubiquitous process that is
responsible for vital physiological responses observed in vivo (eg, immune response, organ …

Metasurface-enhanced infrared spectroscopy in multiwell format for real-time assaying of live cells

SH Huang, G Sartorello, PT Shen, C Xu, O Elemento… - Lab on a Chip, 2023 - pubs.rsc.org
Fourier transform infrared (FTIR) spectroscopy is a popular technique for the analysis of
biological samples, yet its application in characterizing live cells is limited due to the strong …