End-point binding free energy calculation with MM/PBSA and MM/GBSA: strategies and applications in drug design

E Wang, H Sun, J Wang, Z Wang, H Liu… - Chemical …, 2019 - ACS Publications
Molecular mechanics Poisson–Boltzmann surface area (MM/PBSA) and molecular
mechanics generalized Born surface area (MM/GBSA) are arguably very popular methods …

Quantum mechanical continuum solvation models

J Tomasi, B Mennucci, R Cammi - Chemical reviews, 2005 - ACS Publications
This review on continuum solvation models has been preceded in Chemical Reviews by
others addressing the same subject. They are due to Tomasi and Persico1 (published in …

Advances in molecular quantum chemistry contained in the Q-Chem 4 program package

Y Shao, Z Gan, E Epifanovsky, ATB Gilbert… - Molecular …, 2015 - Taylor & Francis
A summary of the technical advances that are incorporated in the fourth major release of the
q-Chem quantum chemistry program is provided, covering approximately the last seven …

Universal solvation model based on solute electron density and on a continuum model of the solvent defined by the bulk dielectric constant and atomic surface …

AV Marenich, CJ Cramer… - The Journal of Physical …, 2009 - ACS Publications
We present a new continuum solvation model based on the quantum mechanical charge
density of a solute molecule interacting with a continuum description of the solvent. The …

Quantum calculation of molecular energies and energy gradients in solution by a conductor solvent model

V Barone, M Cossi - The Journal of Physical Chemistry A, 1998 - ACS Publications
A new implementation of the conductor-like screening solvation model (COSMO) in the
GAUSSIAN94 package is presented. It allows Hartree− Fock (HF), density functional (DF) …

[BOOK][B] Introduction to computational chemistry

F Jensen - 2017 - books.google.com
Introduction to Computational Chemistry 3rd Edition provides a comprehensive account of
the fundamental principles underlying different computational methods. Fully revised and …

Energies, structures, and electronic properties of molecules in solution with the C‐PCM solvation model

M Cossi, N Rega, G Scalmani… - Journal of computational …, 2003 - Wiley Online Library
The conductor‐like solvation model, as developed in the framework of the polarizable
continuum model (PCM), has been reformulated and newly implemented in order to …

The IEF version of the PCM solvation method: an overview of a new method addressed to study molecular solutes at the QM ab initio level

J Tomasi, B Mennucci, E Cancès - Journal of Molecular Structure …, 1999 - Elsevier
The integral equation formalism (IEF) is a recent method (the grounds have been elaborated
at the beginning of 1997) addressed to solve the electrostatic solvation problem at the QM …

New developments in the polarizable continuum model for quantum mechanical and classical calculations on molecules in solution

M Cossi, G Scalmani, N Rega, V Barone - The Journal of Chemical …, 2002 - pubs.aip.org
The polarizable continuum model (PCM), used for the calculation of molecular energies,
structures, and properties in liquid solution has been deeply revised, in order to extend its …

[PDF][PDF] Implicit solvation models: equilibria, structure, spectra, and dynamics

CJ Cramer, DG Truhlar - Chemical Reviews, 1999 - Citeseer
The present review is concerned with continuum and other implicit models of solvation
effects. We will concentrate on the elements required to make such models successful and …