Why is depression more common among women than among men?
C Kuehner - The Lancet Psychiatry, 2017 - thelancet.com
Women are about twice as likely as are men to develop depression during their lifetime. This
Series paper summarises evidence regarding the epidemiology on gender differences in …
Series paper summarises evidence regarding the epidemiology on gender differences in …
Gene–stress–epigenetic regulation of FKBP5: clinical and translational implications
Stress responses and related outcomes vary markedly across individuals. Elucidating the
molecular underpinnings of this variability is of great relevance for develo** individualized …
molecular underpinnings of this variability is of great relevance for develo** individualized …
Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation
Prenatal stress exposure is associated with risk for psychiatric disorders later in life. This
may be mediated in part via enhanced exposure to glucocorticoids (GCs), which are known …
may be mediated in part via enhanced exposure to glucocorticoids (GCs), which are known …
Understanding the molecular mechanisms underpinning gene by environment interactions in psychiatric disorders: the FKBP5 model
Epidemiologic and genetic studies suggest common environmental and genetic risk factors
for a number of psychiatric disorders, including depression, bipolar disorder, and …
for a number of psychiatric disorders, including depression, bipolar disorder, and …
Resilience and the brain: a key role for regulatory circuits linked to social stress and support
Given the high prevalence and burden of mental disorders, fostering the understanding of
protective factors is an urgent issue for translational medicine in psychiatry. The concept of …
protective factors is an urgent issue for translational medicine in psychiatry. The concept of …
Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis
Background Gene-environment interaction contributes to the risks of psychiatric disorders.
Interactions between FKBP5 gene variants and early-life stress may enhance the risk not …
Interactions between FKBP5 gene variants and early-life stress may enhance the risk not …
The FKBP51 glucocorticoid receptor co-chaperone: regulation, function, and implications in health and disease
Among the chaperones and co-chaperones regulating the glucocorticoid receptor (GR),
FK506 binding protein (FKBP) 51 is the most intensely investigated across different …
FK506 binding protein (FKBP) 51 is the most intensely investigated across different …
Differential susceptibility of the develo** brain to contextual adversity and stress
WT Boyce - Neuropsychopharmacology, 2016 - nature.com
A swiftly growing volume of literature, comprising both human and animal studies and
employing both observational and experimental designs, has documented striking individual …
employing both observational and experimental designs, has documented striking individual …
Neurobiological mechanisms of early life adversity, blunted stress reactivity and risk for addiction
Blunted stress reactivity resulting from early exposure to stress during childhood and
adolescence may increase vulnerability to addiction. Early life adversity (ELA) affects brain …
adolescence may increase vulnerability to addiction. Early life adversity (ELA) affects brain …
Prenatal stress and genetic risk: How prenatal stress interacts with genetics to alter risk for psychiatric illness
Risk for neuropsychiatric disorders is complex and includes an individual's internal genetic
endowment and their environmental experiences and exposures. Embryonic development …
endowment and their environmental experiences and exposures. Embryonic development …