Establishing a research agenda for the study and assessment of opioid withdrawal

KE Dunn, EC Strain - The Lancet Psychiatry, 2024 - thelancet.com
The opioid crisis is an international public health concern. Treatments for opioid use
disorder centre largely on the management of opioid withdrawal, an aversive collection of …

Extended-release injection vs sublingual buprenorphine for opioid use disorder with fentanyl use: a post hoc analysis of a randomized clinical trial

EV Nunes, SD Comer, MR Lofwall, SL Walsh… - JAMA Network …, 2024 - jamanetwork.com
Importance Fentanyl has exacerbated the opioid use disorder (OUD) and opioid overdose
epidemic. Data on the effectiveness of medications for OUD among patients using fentanyl …

Buprenorphine-precipitated withdrawal among hospitalized patients using fentanyl

AP Thakrar, PJ Christine, A Siaw-Asamoah… - JAMA Network …, 2024 - jamanetwork.com
Importance Buprenorphine treatment of opioid use disorder (OUD) is safe and effective, but
opioid withdrawal during treatment initiation is associated with poor retention in care. As …

Buprenorphine prescribing characteristics following relaxation of X-waiver training requirements

PJ Christine, RA Chahine, SD Kimmel… - JAMA network …, 2024 - jamanetwork.com
Importance Local-level data are needed to understand whether the relaxation of X-waiver
training requirements for prescribing buprenorphine in April 2021 translated to increased …

Incidence of buprenorphine‐precipitated opioid withdrawal in adults with opioid use disorder: A systematic review

C Gregory, K Yadav, J Linders, L Sikora, D Eagles - Addiction, 2025 - Wiley Online Library
Abstract Background and Aims Buprenorphine is an evidence‐based treatment for opioid
use disorder, and the risk of precipitated withdrawal contributes to its underuse. The goal of …

Withdrawal during outpatient low dose buprenorphine initiation in people who use fentanyl: a retrospective cohort study

BLH Jones, M Geier, J Neuhaus, PO Coffin… - Harm Reduction …, 2024 - Springer
Background Buprenorphine is an effective treatment for opioid use disorder (OUD);
however, buprenorphine initiation can be complicated by withdrawal symptoms including …

Novel uses of methadone under the “72-hour rule” to facilitate transitions of care and low-dose buprenorphine induction in an outpatient bridge clinic

M Shahlapour, S Singh, PJ Christine… - Journal of Addiction …, 2023 - journals.lww.com
Background Federal regulations restrict methadone for opioid use disorder (OUD) treatment
to licensed opioid treatment programs (OTPs). However, providers in other settings can …

Things we do for no reason™: avoiding methadone for opioid withdrawal

M Martin, H Englander… - Journal of hospital …, 2023 - pmc.ncbi.nlm.nih.gov
The “Things We Do for No Reason” series reviews practices, which have become common
parts of hospital care, may provide little value to our patients. Practices reviewed in the …

Challenges with current diagnosis and treatment strategies for precipitated opioid withdrawal in the emergency department and the role of the pharmacist

MJ Glenn, BL Erstad - American Journal of Health-System …, 2025 - academic.oup.com
Purpose To demonstrate the challenges with current diagnosis and treatment strategies for
precipitated opioid withdrawal secondary to naloxone the emergency department (ED) …

Fentanyl, heroin, methamphetamine, and cocaine analyte concentrations in urine drug testing specimens

AS Huhn, P Whitley, BL Bolin, KE Dunn - JAMA Network Open, 2024 - jamanetwork.com
Importance The US is experiencing a protracted drug overdose crisis primarily associated
with exposure to illicitly manufactured fentanyl (IMF), methamphetamine, and cocaine …