Scattering-based light microscopy: from metal nanoparticles to single proteins

L Priest, JS Peters, P Kukura - Chemical reviews, 2021 - ACS Publications
Our ability to detect, image, and quantify nanoscopic objects and molecules with visible light
has undergone dramatic improvements over the past few decades. While fluorescence has …

Interferometric scattering microscopy: seeing single nanoparticles and molecules via Rayleigh scattering

RW Taylor, V Sandoghdar - Nano letters, 2019 - ACS Publications
Fluorescence microscopy has been the workhorse for investigating optical phenomena at
the nanometer scale but this approach confronts several fundamental limits. As a result …

Interferometric scattering microscopy reveals microsecond nanoscopic protein motion on a live cell membrane

RW Taylor, RG Mahmoodabadi, V Rauschenberger… - Nature …, 2019 - nature.com
Many of the biological functions of a cell are dictated by the intricate motion of proteins within
its membrane over a spatial range of nanometres to tens of micrometres and time intervals of …

High-speed nanoscopic tracking of the position and orientation of a single virus

P Kukura, H Ewers, C Müller, A Renn, A Helenius… - Nature …, 2009 - nature.com
Optical studies have revealed that, after binding, virions move laterally on the plasma
membrane, but the complexity of the cellular environment and the drawbacks of …

Interferometric scattering microscopy

G Young, P Kukura - Annual review of physical chemistry, 2019 - annualreviews.org
Interferometric scattering microscopy (iSCAT) is an extremely sensitive imaging method
based on the efficient detection of light scattered by nanoscopic objects. The ability to, at …

GM1 structure determines SV40-induced membrane invagination and infection

H Ewers, W Römer, AE Smith, K Bacia, S Dmitrieff… - Nature cell …, 2010 - nature.com
Abstract Incoming simian virus 40 (SV40) particles enter tight-fitting plasma membrane
invaginations after binding to the carbohydrate moiety of GM1 gangliosides in the host cell …

Optical properties of metallic nanoparticles: manipulating light, heat and forces at the nanoscale

EA Coronado, ER Encina, FD Stefani - Nanoscale, 2011 - pubs.rsc.org
We present to a general readership an overview of the rich variety of phenomena and
applications that arise from the interaction of metallic nanoparticles with light. First, we …

Interferometric scattering microscopy and its combination with single-molecule fluorescence imaging

J Ortega Arroyo, D Cole, P Kukura - Nature protocols, 2016 - nature.com
Interferometric scattering microscopy (iSCAT) is a light scattering-based imaging modality
that offers a unique combination of imaging speed and precision for tracking nanoscopic …

Lipid-mediated endocytosis

H Ewers, A Helenius - Cold Spring Harbor perspectives …, 2011 - cshperspectives.cshlp.org
Receptor-mediated endocytosis is used by a number of viruses and toxins to gain entry into
cells. Some have evolved to use specific lipids in the plasma membrane as their receptors …

A reaction–diffusion within-host HIV model with cell-to-cell transmission

X Ren, Y Tian, L Liu, X Liu - Journal of mathematical biology, 2018 - Springer
In this paper, a reaction–diffusion within-host HIV model is proposed. It incorporates cell
mobility, spatial heterogeneity and cell-to-cell transmission, which depends on the diffusion …