[HTML][HTML] Nrf2-Keap1 signaling in oxidative and reductive stress
I Bellezza, I Giambanco, A Minelli, R Donato - Biochimica et Biophysica …, 2018 - Elsevier
Nrf2 and its endogenous inhibitor, Keap1, function as a ubiquitous, evolutionarily conserved
intracellular defense mechanism to counteract oxidative stress. Sequestered by cytoplasmic …
intracellular defense mechanism to counteract oxidative stress. Sequestered by cytoplasmic …
Muscle fiber type diversification during exercise and regeneration
The plasticity of skeletal muscle can be traced down to extensive metabolic, structural and
molecular remodeling at the single fiber level. Skeletal muscle is comprised of different fiber …
molecular remodeling at the single fiber level. Skeletal muscle is comprised of different fiber …
A growth factor–expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15
Muscle regeneration is the result of the concerted action of multiple cell types driven by the
temporarily controlled phenotype switches of infiltrating monocyte–derived macrophages …
temporarily controlled phenotype switches of infiltrating monocyte–derived macrophages …
Redox control of skeletal muscle regeneration
E Le Moal, V Pialoux, G Juban… - Antioxidants & redox …, 2017 - liebertpub.com
Skeletal muscle shows high plasticity in response to external demand. Moreover, adult
skeletal muscle is capable of complete regeneration after injury, due to the properties of …
skeletal muscle is capable of complete regeneration after injury, due to the properties of …
Roles of Nrf2 in cell proliferation and differentiation
S Murakami, H Motohashi - Free Radical Biology and Medicine, 2015 - Elsevier
Abstract The Keap1-Nrf2 system plays pivotal roles in defense mechanisms by regulating
cellular redox homeostasis. Nrf2 is an inducible transcription factor that activates a battery of …
cellular redox homeostasis. Nrf2 is an inducible transcription factor that activates a battery of …
Dual regulation of transcription factor Nrf2 by Keap1 and by the combined actions of β-TrCP and GSK-3
Nuclear factor-erythroid 2 p45 (NF-E2 p45)-related factor 2 (Nrf2) is a master regulator of
redox homoeostasis that allows cells to adapt to oxidative stress and also promotes cell …
redox homoeostasis that allows cells to adapt to oxidative stress and also promotes cell …
The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic
The transcription factor nuclear factor-erythroid 2 p45-related factor 2 (Nrf2, with gene called
NFE2L2) is a master regulator of the antioxidant response. In the last decade, interest has …
NFE2L2) is a master regulator of the antioxidant response. In the last decade, interest has …
[HTML][HTML] Nrf2 promotes keratinocyte proliferation in psoriasis through up-regulation of keratin 6, keratin 16, and keratin 17
L Yang, X Fan, T Cui, E Dang, G Wang - Journal of Investigative …, 2017 - Elsevier
Psoriasis is a chronic inflammatory skin disease characterized by keratinocyte
hyperproliferation of epidermis. Although hyperproliferation-associated keratins K6, K16 …
hyperproliferation of epidermis. Although hyperproliferation-associated keratins K6, K16 …
Nrf2 in health and disease: current and future clinical implications
The transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) is a major regulator
of oxidative stress defence in the human body. As Nrf2 regulates the expression of a large …
of oxidative stress defence in the human body. As Nrf2 regulates the expression of a large …
Dimethyl fumarate mediates Nrf2-dependent mitochondrial biogenesis in mice and humans
G Hayashi, M Jasoliya, S Sahdeo… - Human molecular …, 2017 - academic.oup.com
The induction of mitochondrial biogenesis could potentially alleviate mitochondrial and
muscle disease. We show here that dimethyl fumarate (DMF) dose-dependently induces …
muscle disease. We show here that dimethyl fumarate (DMF) dose-dependently induces …