Helicobacter pylori induces chronic gastritis and duodenal ulcer in a small fraction of the
colonised population. Three decades after the discovery of H. pylori and disclosure of an …

Background There is a pressing need to understand better the extent and distribution of
antimicrobial resistance on a global scale, to inform development of effective interventions …

A bacterial “systematic evolution of ligands by exponential enrichment” protocol was
developed herein to identify nucleic acid aptamers capable of binding molecules from three …

Background Blood cultures are obtained routinely for infants and young children for the
evaluation for serious bacterial infection. Isolation of organisms that represent possible …

BACKGROUND: Although meningitis is rare in previously healthy term infants, lumbar
puncture is often performed to evaluate for source of illness. This study was performed to …

Background Sepsis is a leading cause of neonatal mortality in low-resource settings. As
facility-based births become more common, the proportion of neonatal deaths due to …

Background Pediatric bacterial meningitis (PBM) remains a devastating disease that causes
substantial neurological morbidity and mortality worldwide. However, there are few large …

Background Multiple blood cultures have been shown to improve pathogen yield and
antimicrobial stewardship for adult patients with suspected serious bacterial infection (SBI) …

Introduction Sepsis is the leading cause of infectious morbidity and mortality among
hospitalized neonates. In high-resource pediatric and adult intensive care units, use of …

The multisite community-based study, Aetiology of Neonatal Infection in South Asia (ANISA),
uses blood culture as the gold standard for identifying the etiology of neonatal infection …