Active turbulence

R Alert, J Casademunt, JF Joanny - Annual Review of …, 2022 - annualreviews.org
Active fluids exhibit spontaneous flows with complex spatiotemporal structure, which have
been observed in bacterial suspensions, sperm cells, cytoskeletal suspensions, self …

Physical models of collective cell migration

R Alert, X Trepat - Annual Review of Condensed Matter Physics, 2020 - annualreviews.org
Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …

Active wetting of epithelial tissues

C Pérez-González, R Alert, C Blanch-Mercader… - Nature physics, 2019 - nature.com
Abstract Development, regeneration and cancer involve drastic transitions in tissue
morphology. In analogy with the behaviour of inert fluids, some of these transitions have …

Universal scaling of active nematic turbulence

R Alert, JF Joanny, J Casademunt - Nature Physics, 2020 - nature.com
A landmark of turbulence is the emergence of universal scaling laws, such as Kolmogorov's
E (q)~ q− 5∕ 3 scaling of the kinetic energy spectrum of inertial turbulence with the …

Turbulent dynamics of epithelial cell cultures

C Blanch-Mercader, V Yashunsky, S Garcia, G Duclos… - Physical review …, 2018 - APS
We investigate the large length and long time scales collective flows and structural
rearrangements within in vitro human bronchial epithelial cell (HBEC) cultures. Activity …

Mesoscale physical principles of collective cell organization

X Trepat, E Sahai - Nature Physics, 2018 - nature.com
We review recent evidence showing that cell and tissue dynamics are governed by
mesoscale physical principles. These principles can be understood in terms of simple state …

Material approaches to active tissue mechanics

W **, TB Saw, D Delacour, CT Lim… - Nature Reviews Materials, 2019 - nature.com
Communities of epithelial cells communicate through intercellular interactions, allowing
them to coordinate their motility, which plays a key role in homeostasis, morphogenesis and …

Theory of mechanochemical patterning and optimal migration in cell monolayers

D Boocock, N Hino, N Ruzickova, T Hirashima… - Nature physics, 2021 - nature.com
Collective cell migration offers a rich field of study for non-equilibrium physics and cellular
biology, revealing phenomena such as glassy dynamics, pattern formation and active …

Biological tissues as active nematic liquid crystals

TB Saw, W **, B Ladoux, CT Lim - Advanced materials, 2018 - Wiley Online Library
Live tissues can self‐organize and be described as active materials composed of cells that
generate active stresses through continuous injection of energy. In vitro reconstituted …

Collective cell migration without proliferation: density determines cell velocity and wave velocity

S Tlili, E Gauquelin, B Li, O Cardoso… - Royal Society …, 2018 - royalsocietypublishing.org
Collective cell migration contributes to embryogenesis, wound healing and tumour
metastasis. Cell monolayer migration experiments help in understanding what determines …