In recent years there has been a growing interest in the field of non-coding RNA. This surge
is a direct consequence of the discovery of a huge number of new non-coding genes and of …

Background RNA secondary structure comparison is a fundamental task for several studies,
among which are RNA structure prediction and evolution. The comparison can currently be …

A two-level particle swarm optimization (TL-PSO) algorithm is proposed for training
stochastic context-sensitive hidden Markov model (cs-HMM), that addresses a thrust area of …

Modern biological databases comprise not only data, but also sophisticated query facilities
and bioinformatics data analysis tools. This book provides an exploration through the world …

Background RNA pseudoknots play important roles in many biological processes. Previous
methods for comparative pseudoknot analysis mainly focus on simultaneous folding and …

Hong Kong's bioinformatics sector is attaining new heights in combination with its economic
boom and the predominance of the working-age group in its population. Factors such as a …

The biological function of an RNA molecule depends on its structure. The objective of the
alignment is finding the homology between two or more RNA secondary structures. Knowing …

This dissertation addresses data mining in bioinformatics by investigating two important
problems, namely peak detection and structure matching. Peak detection is useful for …