Chiral self-assembly of peptides: Toward the design of supramolecular polymers with enhanced chemical and biological functions

Y Shen, Y Wang, IW Hamley, W Qi, R Su… - Progress in Polymer …, 2021 - Elsevier
Chirality is one of the most important structural features in biological systems. Peptides, as a
class of small biomolecules, can self-assemble into various chiral supramolecular polymers …

Integrating Computation, Experiment, and Machine Learning in the Design of Peptide‐Based Supramolecular Materials and Systems

M Ramakrishnan, A van Teijlingen… - Angewandte Chemie …, 2023 - Wiley Online Library
Interest in peptide‐based supramolecular materials has grown extensively since the 1980s
and the application of computational methods has paralleled this. These methods contribute …

Spontaneous and Selective Peptide Elongation in Water Driven by Aminoacyl Phosphate Esters and Phase Changes

K Dai, MD Pol, L Saile, A Sharma, B Liu… - Journal of the …, 2023 - ACS Publications
Nature chose phosphates to activate amino acids, where reactive intermediates and
complex machinery drive the construction of polyamides. Outside of biology, the pathways …

Controlling the Assembly of Cellulose‐Based Oligosaccharides through Sequence Modifications

N Hribernik, D Vargová, MCS Dal Colle… - Angewandte Chemie …, 2023 - Wiley Online Library
Peptides and nucleic acids with programmable sequences are widely explored for the
production of tunable, self‐assembling functional materials. Herein we demonstrate that the …

Modulation of mechanical properties of short bioinspired peptide materials by single amino-acid mutations

SH Hiew, Y Lu, H Han, RA Gonçalves… - Journal of the …, 2023 - ACS Publications
The occurrence of modular peptide repeats in load-bearing (structural) proteins is common
in nature, with distinctive peptide sequences that often remain conserved across different …

Chiral-engineered supraparticles: Emerging tools for drug delivery

M Rahman, WH Almalki, O Afzal, ASA Altamimi… - Drug Discovery …, 2023 - Elsevier
Highlights•Molecular chirality recognized in pharmacokinetics and pharmacodynamics.•
Supramolecular polymers (SPs) are excellent systems in biological system assembly.•Chiral …

Peptide Stereochemistry Effects from pKa-Shift to Gold Nanoparticle Templating in a Supramolecular Hydrogel

S Adorinni, S Gentile, O Bellotto, S Kralj, E Parisi… - ACS …, 2024 - ACS Publications
The divergent supramolecular behavior of a series of tripeptide stereoisomers was
elucidated through spectroscopic, microscopic, crystallographic, and computational …

[HTML][HTML] Nanostructured ceria: Biomolecular templates and (bio) applications

P Rozhin, M Melchionna, P Fornasiero, S Marchesan - Nanomaterials, 2021 - mdpi.com
Ceria (CeO2) nanostructures are well-known in catalysis for energy and environmental
preservation and remediation. Recently, they have also been gaining momentum for …

Computational approaches for understanding and predicting the self-assembled peptide hydrogels

P Zhou, C Yuan, X Yan - Current Opinion in Colloid & Interface Science, 2022 - Elsevier
Self-assembled peptide hydrogel is a promising biomaterial and has been widely applied in
many fields. As a typical self-assembly material, peptide hydrogel exhibits properties …

Self-assembled peptide nanostructures for ECM biomimicry

D Marin, S Marchesan - Nanomaterials, 2022 - mdpi.com
Proteins are functional building blocks of living organisms that exert a wide variety of
functions, but their synthesis and industrial production can be cumbersome and expensive …