Transition metal complexes and photodynamic therapy from a tumor-centered approach: challenges, opportunities, and highlights from the development of TLD1433

S Monro, KL Colon, H Yin, J Roque III, P Konda… - Chemical …, 2018 - ACS Publications
Transition metal complexes are of increasing interest as photosensitizers in photodynamic
therapy (PDT) and, more recently, for photochemotherapy (PCT). In recent years, Ru (II) …

Photoelectrochemical DNA biosensors

WW Zhao, JJ Xu, HY Chen - Chemical reviews, 2014 - ACS Publications
Biosensors could register a biological event and convert it into a measurable signal with
specific biosensing elements and transducers. 1− 5 A DNA biosensor is a device that …

Ruthenium (II) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics

MR Gill, JA Thomas - Chemical Society Reviews, 2012 - pubs.rsc.org
In the last few decades, coordination complexes based on d6 metal centres and polypyridyl
ligand architectures been developed as structure-and site-specific reversible DNA binding …

Near-infrared absorbing Ru (ii) complexes act as immunoprotective photodynamic therapy (PDT) agents against aggressive melanoma

LM Lifshits, JA Roque III, P Konda, S Monro… - Chemical …, 2020 - pubs.rsc.org
Mounting evidence over the past 20 years suggests that photodynamic therapy (PDT), an
anticancer modality known mostly as a local treatment, has the capacity to invoke a systemic …

Marked improvement in photoinduced cell death by a new tris-heteroleptic complex with dual action: singlet oxygen sensitization and ligand dissociation

BA Albani, B Pena, NA Leed… - Journal of the …, 2014 - ACS Publications
The new tris-heteroleptic complex [Ru (bpy)(dppn)(CH3CN) 2] 2+(3, bpy= 2, 2′-bipyridine,
dppn= benzo [i] dipyrido [3, 2-a; 2′, 3′-c] phenazine) was synthesized and characterized …

DNA Intercalating RuII Polypyridyl Complexes as Effective Photosensitizers in Photodynamic Therapy

C Mari, V Pierroz, R Rubbiani, M Patra… - … A European Journal, 2014 - Wiley Online Library
Six substitutionally inert [RuII (bipy) 2dppz] 2+ derivatives (bipy= 2, 2′‐bipyridine, dppz=
dipyrido [3, 2‐a: 2′, 3′‐c] phenazine) bearing different functional groups on the dppz …

Ruthenium (II) complexes with dppz: from molecular photoswitch to biological applications

G Li, L Sun, L Ji, H Chao - Dalton Transactions, 2016 - pubs.rsc.org
The DNA photoswitch [Ru (bpy) 2dppz] 2+(bpy= 2, 2′-bipyridine, dppz= dipyrido [3, 2-a:
2′, 3′-c] phenazine) has attracted much attention and become a powerful tool for studying …

Ruthenium(II) Polyimine Complexes with a Long‐Lived 3IL Excited State or a 3MLCT/3IL Equilibrium: Efficient Triplet Sensitizers for Low‐Power Upconversion

S Ji, W Wu, W Wu, H Guo, J Zhao - Angewandte Chemie International …, 2011 - infona.pl
Up, up, and away! The long‐lived 3 IL excited states of Ru II polyimine complexes were
found to be more efficient in sensitizing upconversion based on triplet–triplet annihilation …

Efficient DNA photocleavage by [Ru (bpy) 2 (dppn)] 2+ with visible light

Y Sun, LE Joyce, NM Dickson, C Turro - Chemical communications, 2010 - pubs.rsc.org
The population and reactivity of two low-lying excited states in [Ru (bpy) 2 (dppn)] 2+(bpy= 2,
2′-bipyridine, dppn= benzo [i] dipyrido [3, 2-a: 2′, 3′-c] phenazine), a weakly emissive …

Factors that Impact Photochemical Cage Escape Yields

MJ Goodwin, JC Dickenson, A Ripak, AM Deetz… - Chemical …, 2024 - ACS Publications
The utilization of visible light to mediate chemical reactions in fluid solutions has
applications that range from solar fuel production to medicine and organic synthesis. These …