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Intestinal in vitro and ex vivo Models to Study Host-Microbiome Interactions and Acute Stressors
The gut microbiome is extremely important for maintaining homeostasis with host intestinal
epithelial, neuronal, and immune cells and this host-microbe interaction is critical during …
epithelial, neuronal, and immune cells and this host-microbe interaction is critical during …
The porcine innate immune system: an update
KH Mair, C Sedlak, T Käser, A Pasternak… - Developmental & …, 2014 - Elsevier
Over the last few years, we have seen an increasing interest and demand for pigs in
biomedical research. Domestic pigs (Sus scrofa domesticus) are closely related to humans …
biomedical research. Domestic pigs (Sus scrofa domesticus) are closely related to humans …
Rotavirus interactions with host intestinal epithelial cells
Rotavirus (RV) is the foremost enteric pathogen associated with severe diarrheal illness in
young children (< 5years) and animals worldwide. RV primarily infects mature enterocytes in …
young children (< 5years) and animals worldwide. RV primarily infects mature enterocytes in …
[HTML][HTML] Human-derived probiotic Lactobacillus reuteri strains differentially reduce intestinal inflammation
Y Liu, NY Fatheree, N Mangalat… - American Journal of …, 2010 - journals.physiology.org
Lactobacillus reuteri (L. reuteri) is a probiotic that inhibits the severity of enteric infections
and modulates the immune system. Human-derived L. reuteri strains DSM17938, ATCC …
and modulates the immune system. Human-derived L. reuteri strains DSM17938, ATCC …
Type III interferon restriction by porcine epidemic diarrhea virus and the role of viral protein nsp1 in IRF1 signaling
Type III interferons (IFNs) play a vital role in maintaining the antiviral state of the mucosal
epithelial surface in the gut, and in turn, enteric viruses may have evolved to evade the type …
epithelial surface in the gut, and in turn, enteric viruses may have evolved to evade the type …
Porcine IPEC-J2 intestinal epithelial cells in microbiological investigations
IPEC-J2 cells are porcine intestinal columnar epithelial cells that were isolated from
neonatal piglet mid-jejunum. This cell line forms polarized monolayers with high …
neonatal piglet mid-jejunum. This cell line forms polarized monolayers with high …
Individual and combined cytotoxic effects of Fusarium toxins (deoxynivalenol, nivalenol, zearalenone and fumonisins B1) on swine jejunal epithelial cells
Fusarium mycotoxins occur worldwide in foods such as cereals and animal forages, leading
to acute and chronic exposures in human and animals. Intestinal epithelial cells (IECs) are …
to acute and chronic exposures in human and animals. Intestinal epithelial cells (IECs) are …
Polyphenols from brown seaweeds as a potential antimicrobial agent in animal feeds
Seaweeds offer a natural source of antimicrobials that may help curb antibiotic resistance in
livestock. The antibacterial activity of phlorotannin extracts isolated from two brown …
livestock. The antibacterial activity of phlorotannin extracts isolated from two brown …
Protective effects of Lactobacillus plantarum on epithelial barrier disruption caused by enterotoxigenic Escherichia coli in intestinal porcine epithelial cells
Y Wu, C Zhu, Z Chen, Z Chen, W Zhang, X Ma… - Veterinary immunology …, 2016 - Elsevier
Tight junctions (TJs) play an important role in maintaining the mucosal barrier function and
gastrointestinal health of animals. Lactobacillus plantarum (L. plantarum) was reported to …
gastrointestinal health of animals. Lactobacillus plantarum (L. plantarum) was reported to …
Short-chain fatty acid butyrate, a breast milk metabolite, enhances immature intestinal barrier function genes in response to inflammation in vitro and in vivo
Y Gao, B Davis, W Zhu, N Zheng… - American Journal of …, 2021 - journals.physiology.org
Infants born under 1,500 g have an increased incidence of necrotizing enterocolitis in the
ileum and the colon, which is a life-threatening intestinal necrosis. This is in part due to …
ileum and the colon, which is a life-threatening intestinal necrosis. This is in part due to …