Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein

MA Simon, I Iordanov, A Szollosi, L Csanády - Elife, 2023 - elifesciences.org
CFTR, the anion channel mutated in cystic fibrosis patients, is a model ABC protein whose
ATP-driven conformational cycle is observable at single-molecule level in patch-clamp …