The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

The freshwater polyp Hydra provides a potent model system for investigating the conditions
that promote wound healing, reactivation of a developmental process and, ultimately …

Epithelial monolayers are two-dimensional cell sheets which compartmentalize the body
and organs of multicellular organisms. Their morphogenesis during development or …

Tissue deformation mediated by collective cell contractility is a signature characteristic of
animals. In most animals, fast and reversible contractions of muscle cells mediate behavior …

During development, epithelial sheets sculpt organs by folding, either apically or basally,
into complex 3D structures. Given the presence of actomyosin networks and cell adhesion …

Nematocysts are generated by secretion of proteins into a post-Golgi compartment. They
consist of a capsule that elongates into a long tube, which is coiled inside the capsule matrix …

Non-bilaterian animals consist of four phyla; Porifera, Cnidaria, Ctenophora, and Placozoa.
These early-diverging animals are crucial for understanding the evolution of the entire …

Morphogenesis is a shape-building process during development of multicellular organisms.
During this process, the establishment and modulation of cell-cell contacts play an important …

Hydra vulgaris exhibits a remarkable capacity to reassemble its body plan from a disordered
aggregate of cells. Reassembly begins by sorting two epithelial cell types, endoderm and …

Active curling of epithelial tissues, as an indispensable component of developmental
morphogenesis, occurs frequently both in vivo and in vitro microenvironments. Deciphering …