The mammalian forebrain is constructed from ensembles of neurons that form local
microcircuits giving rise to the exquisite cognitive tasks the mammalian brain can perform …

Although Lorente de No'recognized the anatomical distinction of the hippocampal Cornu
Ammonis (CA) 2 region, it had, until recently, been assigned no unique function. Its location …

Input-timing-dependent plasticity (ITDP) is a circuit-based synaptic learning rule by which
paired activation of entorhinal cortical (EC) and Schaffer collateral (SC) inputs to …

A quantitative description of the hippocampal formation synaptic architecture is essential for
understanding the neural mechanisms of episodic memory. Yet the existing knowledge of …

The CA2 region of the mammalian hippocampus is a unique region with its own distinctive
properties, inputs and pathologies. Disruption of inhibitory circuits in this region appears to …

Examining the function of individual human hippocampal subfields remains challenging
because of their small sizes and convoluted structures. Previous human fMRI studies at 3 T …

Systematically organizing the anatomical, molecular, and physiological properties of cortical
neurons is important for understanding their computational functions. Hippocampome. org …

The proximodistal axis is considered a major organizational principle of the hippocampus. At
the interface between the hippocampus and other brain structures, CA2 apparently breaks …

A significant proportion of temporal lobe epilepsy (TLE) patients experience drug-resistant
seizures associated with mesial temporal sclerosis, in which there is extensive cell loss in …

The hippocampus is a central region in the coding of spatial, temporal and episodic memory.
Recent discoveries have revealed surprising and complex roles of the small area CA2 in …