Immunopathogenesis of Behcet's disease

B Tong, X Liu, J **ao, G Su - Frontiers in immunology, 2019 - frontiersin.org
Behcet's disease (BD) is a chronic systemic inflammatory vasculitis of unknown etiology
characterized by recurrent episodes of oral aphthous ulcers, genital ulcers, skin lesions …

Behçet's disease: new insights into pathophysiology, clinical features and treatment options

A Greco, A De Virgilio, M Ralli, A Ciofalo, P Mancini… - Autoimmunity …, 2018 - Elsevier
Behçet's disease (BD) is a rare systemic vasculitis characterized by oral aphthous ulcers,
genital ulcers, ocular lesions and other systemic manifestations. BD occurs most frequently …

Molecular mechanisms of action of anti-TNF-α agents–Comparison among therapeutic TNF-α antagonists

H Mitoma, T Horiuchi, H Tsukamoto, N Ueda - Cytokine, 2018 - Elsevier
Tumor necrosis factor (TNF)-α is a potent pro-inflammatory and pathological cytokines in
inflammatory diseases such as rheumatoid arthritis and inflammatory bowel diseases. Anti …

[HTML][HTML] The role of cytokines in predicting the response and adverse events related to immune checkpoint inhibitors

M Wang, X Zhai, J Li, J Guan, S Xu, YY Li… - Frontiers in …, 2021 - frontiersin.org
Recently, the overall survival (OS) and progression-free survival (PFS) of patients with
advanced cancer has been significantly improved due to the application of immune …

Expert panel recommendations for the use of anti–tumor necrosis factor biologic agents in patients with ocular inflammatory disorders

G Levy-Clarke, DA Jabs, RW Read, JT Rosenbaum… - Ophthalmology, 2014 - Elsevier
Topic To provide recommendations for the use of anti-tumor necrosis factor α (TNF-α)
biologic agents in patients with ocular inflammatory disorders. Clinical Relevance Ocular …

Diagnosis and management of Neuro-Behçet's disease: international consensus recommendations

S Kalra, A Silman, G Akman-Demir, S Bohlega… - Journal of …, 2014 - Springer
Neuro-Behçet's disease (NBD) is one of the more serious manifestations of Behçet's disease
(BD), which is a relapsing inflammatory multisystem disease with an interesting …

Efficacy of anti-TNF alpha in severe and/or refractory Behçet's disease: multicenter study of 124 patients

H Vallet, S Riviere, A Sanna, A Deroux, G Moulis… - Journal of …, 2015 - Elsevier
Objective To report the efficacy and safety of anti-TNF agents in patients with severe and/or
refractory manifestations of Behçet's disease (BD). Methods We performed a multicenter …

[HTML][HTML] Immunopathogenesis of Behçet's disease and treatment modalities

TB Van der Houwen, PM Van Hagen… - Seminars in Arthritis and …, 2022 - Elsevier
Introduction Behçet's disease (BD) is an auto-inflammatory disease, primarily characterized
by recurrent painful mucocutaneous ulcerations. Methods A literature search was performed …

Advances in the treatment of Behcet's disease

F Alibaz-Oner, H Direskeneli - Current rheumatology reports, 2021 - Springer
Abstract Purpose of Review To assess current management of Behcet's disease (BD).
Controversies on therapeutic approaches to different manifestations, whether conventional …

Thrombosis in vasculitis: from pathogenesis to treatment

G Emmi, E Silvestri, D Squatrito, A Amedei, E Niccolai… - Thrombosis journal, 2015 - Springer
In recent years, the relationship between inflammation and thrombosis has been deeply
investigated and it is now clear that immune and coagulation systems are functionally …