Roles of macrophages on ulcerative colitis and colitis-associated colorectal cancer

M Zhang, X Li, Q Zhang, J Yang, G Liu - Frontiers in immunology, 2023 - frontiersin.org
Colitis-associated colorectal cancer is the most serious complication of ulcerative colitis.
Long-term chronic inflammation increases the incidence of CAC in UC patients. Compared …

Non-coding RNAs and macrophage interaction in tumor progression

M Entezari, M Sadrkhanloo, M Rashidi, SE Asnaf… - Critical reviews in …, 2022 - Elsevier
The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor
malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage …

Targeting AhR as a novel therapeutic modality against inflammatory diseases

AS Cannon, PS Nagarkatti, M Nagarkatti - International Journal of …, 2021 - mdpi.com
For decades, activation of Aryl Hydrocarbon Receptor (AhR) was excluded from
consideration as a therapeutic approach due to the potential toxic effects of AhR ligands and …

The lncRNAs UCA1 and CRNDE target miR-145/TLR4/NF-қB/TNF-α axis in acetic acid-induced ulcerative colitis model: The beneficial role of 3, 3-diindolylmethane

NA El-Boghdady, S Abd El-Hakk… - International …, 2023 - Elsevier
Introduction Ulcerative colitis (UC) is a chronic disease that alters the colonic and rectal
mucosa. The high prevalence rates of UC make it a worldwide healthcare problem …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

[HTML][HTML] Mechanisms of microRNA-132 in central neurodegenerative diseases: A comprehensive review

C Mu, M Gao, W Xu, X Sun, T Chen, H Xu… - Biomedicine & …, 2024 - Elsevier
Abstracts MicroRNA-132 (miR-132) is a highly conserved molecule that plays a crucial
regulatory role in central nervous system (CNS) disorders. The expression levels of miR-132 …

Activation of aryl hydrocarbon receptor signaling by a novel agonist ameliorates autoimmune encephalomyelitis

A Abdullah, M Maged, I Hairul-Islam M, A Osama I… - PloS one, 2019 - journals.plos.org
Background Multiple sclerosis (MS) is a widespread neurological autoimmune disease that
includes episodes of demyelination in the central nervous system (CNS). The accumulated …

Heparin-binding EGF-like growth factor via miR-126 controls tumor formation/growth and the proteolytic niche in murine models of colorectal and colitis-associated …

Y Salama, S Munakata, T Osada, S Takahashi… - Cell Death & …, 2024 - nature.com
MicroRNAs, including the tumor-suppressor miR-126 and the oncogene miR-221, regulate
tumor formation and growth in colitis-associated cancer (CAC) and colorectal cancer (CRC) …

The Role of miRNA‐132 against apoptosis and oxidative stress in heart failure

X Liu, Z Tong, K Chen, X Hu, H **… - Biomed Research …, 2018 - Wiley Online Library
Objective. To explore the effect of microRNA‐132 of heart failure and provide theoretical
guidance for clinical treatment of heart failure (HF). Methods. Peripheral blood was collected …

[HTML][HTML] Does NLRP3 inflammasome and aryl hydrocarbon receptor play an interlinked role in bowel inflammation and colitis-associated colorectal cancer?

IQH Ngui, AP Perera, R Eri - Molecules, 2020 - mdpi.com
Inflammation is a hallmark in many forms of cancer; with colitis-associated colorectal cancer
(CAC) being a progressive intestinal inflammation due to inflammatory bowel disease (IBD) …