Effects of polyethylene glycol on the surface of nanoparticles for targeted drug delivery

L Shi, J Zhang, M Zhao, S Tang, X Cheng, W Zhang… - Nanoscale, 2021 - pubs.rsc.org
The rapid development of drug nanocarriers has benefited from the surface hydrophilic
polymers of particles, which has improved the pharmacokinetics of the drugs. Polyethylene …

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

JS Suk, Q Xu, N Kim, J Hanes, LM Ensign - Advanced drug delivery reviews, 2016 - Elsevier
Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …

Water-dispersible PEG-curcumin/amine-functionalized covalent organic framework nanocomposites as smart carriers for in vivo drug delivery

G Zhang, X Li, Q Liao, Y Liu, K **, W Huang… - Nature …, 2018 - nature.com
Covalent organic frameworks (COFs) as drug-delivery carriers have been mostly evaluated
in vitro due to the lack of COFs nanocarriers that are suitable for in vivo studies. Here we …

Gold nanomaterials at work in biomedicine

X Yang, M Yang, B Pang, M Vara, Y **a - Chemical reviews, 2015 - ACS Publications
Gold is a precious metal with a characteristic bright and beautiful hue known as the golden
yellow color.(1) As of 2012, a total of 174,100 tons of Au has been mined in human history …

Engineered nanoparticles for drug delivery in cancer therapy

T Sun, YS Zhang, B Pang, DC Hyun… - Nanomaterials and …, 2021 - taylorfrancis.com
In medicine, nanotechnology has sparked a rapidly growing interest as it promises to solve a
number of issues associated with conventional therapeutic agents, including their poor …

SERS nanoparticles in medicine: from label-free detection to spectroscopic tagging

LA Lane, X Qian, S Nie - Chemical reviews, 2015 - ACS Publications
The development of diagnostic and therapeutic nanoparticles for biomedical applications is
of broad current interest in science, engineering, and medicine. The fundamental basis is …

25th anniversary article: galvanic replacement: a simple and versatile route to hollow nanostructures with tunable and well‐controlled properties

X **a, Y Wang, A Ruditskiy, Y **a - Advanced Materials, 2013 - Wiley Online Library
This article provides a progress report on the use of galvanic replacement for generating
complex hollow nanostructures with tunable and well‐controlled properties. We begin with a …

Synthesis, chemical–physical characterization, and biomedical applications of functional gold nanoparticles: A review

I Ielo, G Rando, F Giacobello, S Sfameni, A Castellano… - Molecules, 2021 - mdpi.com
Relevant properties of gold nanoparticles, such as stability and biocompatibility, together
with their peculiar optical and electronic behavior, make them excellent candidates for …

PEGylated PRINT nanoparticles: the impact of PEG density on protein binding, macrophage association, biodistribution, and pharmacokinetics

JL Perry, KG Reuter, MP Kai, KP Herlihy, SW Jones… - Nano …, 2012 - ACS Publications
In this account, we varied PEGylation density on the surface of hydrogel PRINT
nanoparticles and systematically observed the effects on protein adsorption, macrophage …

Gold nanoparticles in combinatorial cancer therapy strategies

J Beik, M Khateri, Z Khosravi, SK Kamrava… - Coordination Chemistry …, 2019 - Elsevier
Cancer is one of the most important health issues, which is the second leading cause of
death in the world. Conventional cancer therapy methods encounter with serious drawbacks …