Hypertension and the risk of dementia
C Sierra - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Hypertension, particularly midlife high blood pressure, has been related to a higher risk of
cognitive decline and dementia, including Alzheimer disease. However, these associations …
cognitive decline and dementia, including Alzheimer disease. However, these associations …
[HTML][HTML] Can exercise training teach us how to treat Alzheimer's disease?
AM Huuha, CS Norevik, JBN Moreira… - Ageing research …, 2022 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia and there is currently no
cure. Novel approaches to treat AD and curb the rapidly increasing worldwide prevalence …
cure. Novel approaches to treat AD and curb the rapidly increasing worldwide prevalence …
[HTML][HTML] An integrated view on vascular dysfunction in Alzheimer's disease
J Klohs - Neurodegenerative Diseases, 2019 - karger.com
Background: Cerebrovascular disease is a common comorbidity in patients with Alzheimer's
disease (AD). It is believed to contribute additively to the cognitive impairment and to lower …
disease (AD). It is believed to contribute additively to the cognitive impairment and to lower …
[HTML][HTML] Cerebral small vessel disease in sporadic and familial Alzheimer disease
Alzheimer disease (AD) is the most common cause of dementia. Biological definitions of AD
are limited to the cerebral burden of amyloid β plaques, neurofibrillary pathology, and …
are limited to the cerebral burden of amyloid β plaques, neurofibrillary pathology, and …
Attenuating vascular stenosis-induced astrogliosis preserves white matter integrity and cognitive function
Background Chronic cerebral hypoperfusion (CCH) causes white matter damage and
cognitive impairment, in which astrogliosis is the major pathology. However, underlying …
cognitive impairment, in which astrogliosis is the major pathology. However, underlying …
Hypertensive adults exhibit lower myelin content: a multicomponent relaxometry and diffusion magnetic resonance imaging study
BACKGROUND: It is unknown whether hypertension plays any role in cerebral myelination.
To fill this knowledge gap, we studied 90 cognitively unimpaired adults, age range 40 to 94 …
To fill this knowledge gap, we studied 90 cognitively unimpaired adults, age range 40 to 94 …
Microvascular dysfunction as a possible link between heart failure and cognitive dysfunction
BACKGROUND: Microvascular function in the brain and heart may play an important role in
the course of patients with heart failure (HF), but its relationship with ventricular and …
the course of patients with heart failure (HF), but its relationship with ventricular and …
Associations between arterial stiffening and brain structure, perfusion, and cognition in the Whitehall II Imaging Sub-study: A retrospective cohort study
Background Aortic stiffness is closely linked with cardiovascular diseases (CVDs), but recent
studies suggest that it is also a risk factor for cognitive decline and dementia. However, the …
studies suggest that it is also a risk factor for cognitive decline and dementia. However, the …
[HTML][HTML] Inter-and intra-individual variation in brain structural-cognition relationships in aging
The sources of inter-and intra-individual variability in age-related cognitive decline remain
poorly understood. We examined the association between 20-year trajectories of cognitive …
poorly understood. We examined the association between 20-year trajectories of cognitive …
[HTML][HTML] Dysregulated cerebral blood flow, rather than gray matter Volume, exhibits stronger correlations with blood inflammatory and lipid markers in depression
L Kang, W Wang, Z Nie, Q Gong, L Yao, D **ang… - NeuroImage: Clinical, 2024 - Elsevier
Arterial spin labeling (ASL) can be used to detect differences in perfusion for multiple brain
regions thought to be important in major depressive disorder (MDD). However, the potential …
regions thought to be important in major depressive disorder (MDD). However, the potential …