Reproductive tract extracellular vesicles are sufficient to transmit intergenerational stress and program neurodevelopment
Extracellular vesicles (EVs) are a unique mode of intercellular communication capable of
incredible specificity in transmitting signals involved in cellular function, including germ cell …
incredible specificity in transmitting signals involved in cellular function, including germ cell …
Is the epididymis a series of organs placed side by side?
The mammalian epididymis is more than a highly convoluted tube divided into four regions:
initial segment, caput, corpus and cauda. It is a highly segmented structure with each …
initial segment, caput, corpus and cauda. It is a highly segmented structure with each …
Profiling of epididymal small non‐protein‐coding RNA s
Background Our understanding of epididymal physiology and function has been
transformed over the three decades in which the International Meeting Series on the …
transformed over the three decades in which the International Meeting Series on the …
Characterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenome
Recent evidence has shown that the sperm epigenome is vulnerable to dynamic
modifications arising from a variety of paternal environment exposures and that this legacy …
modifications arising from a variety of paternal environment exposures and that this legacy …
Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation
The functional maturation of spermatozoa that is necessary to achieve fertilization occurs as
these cells transit through the epididymis, a highly specialized region of the male …
these cells transit through the epididymis, a highly specialized region of the male …
Global profiling of the proteomic changes associated with the post-testicular maturation of mouse spermatozoa
Spermatozoa acquire fertilization potential during passage through a highly specialized
region of the extratesticular ductal system known as the epididymis. In the absence of de …
region of the extratesticular ductal system known as the epididymis. In the absence of de …
Spatio-temporal landscape of mouse epididymal cells and specific mitochondria-rich segments defined by large-scale single-cell RNA-seq
J Shi, KL Fok, P Dai, F Qiao, M Zhang, H Liu, M Sang… - Cell Discovery, 2021 - nature.com
Spermatozoa acquire their fertilizing ability and forward motility during epididymal transit,
suggesting the importance of the epididymis. Although the cell atlas of the epididymis was …
suggesting the importance of the epididymis. Although the cell atlas of the epididymis was …
Analysis of the small non-protein-coding RNA profile of mouse spermatozoa reveals specific enrichment of piRNAs within mature spermatozoa
Post-testicular sperm maturation and storage within the epididymis is a key determinant of
gamete quality and fertilization competence. Here we demonstrate that mouse spermatozoa …
gamete quality and fertilization competence. Here we demonstrate that mouse spermatozoa …
[HTML][HTML] Epididymal mRNA and miRNA transcriptome analyses reveal important genes and miRNAs related to sperm motility in roosters
K **ng, Y Chen, L Wang, X Lv, Z Li, X Qi, X Wang… - Poultry Science, 2022 - Elsevier
Sperm motility is a crucial trait in chicken production, and the epididymis is an essential
organ in the reproductive system. Currently, the molecular mechanisms underlying sperm …
organ in the reproductive system. Currently, the molecular mechanisms underlying sperm …
Mouse quiescin sulfhydryl oxidases exhibit distinct epididymal luminal distribution with segment-specific sperm surface associations
TE Wang, SH Li, S Minabe, AL Anderson… - Biology of …, 2018 - academic.oup.com
Sulfhydryl oxidation is part of the sperm maturation process essential for the acquisition of
sperm fertilization competency and its structural stabilization; however, the specific sulfhydryl …
sperm fertilization competency and its structural stabilization; however, the specific sulfhydryl …