Distinct medial orbitofrontal–striatal circuits support dissociable component processes of risk/reward decision-making

NL Jenni, G Rutledge, SB Floresco - Journal of Neuroscience, 2022 - Soc Neuroscience
The medial orbitofrontal cortex (mOFC) regulates a variety of cognitive functions, including
refining action selection involving reward uncertainty. This region sends projections to …

Front and center: Maturational dysregulation of frontal lobe functional neuroanatomic connections in attention deficit hyperactivity disorder

G Leisman, R Melillo - Frontiers in neuroanatomy, 2022 - frontiersin.org
Frontal lobe function may not universally explain all forms of attention deficit hyperactivity
disorder (ADHD) but the frontal lobe hypothesis described supports an internally consistent …

Medial orbitofrontal cortex dopamine D1/D2 receptors differentially modulate distinct forms of probabilistic decision-making

NL Jenni, YT Li, SB Floresco - Neuropsychopharmacology, 2021 - nature.com
Efficient decision-making involves weighing the costs and benefits associated with different
actions and outcomes to maximize long-term utility. The medial orbitofrontal cortex (mOFC) …

Basal forebrain mediates motivational recruitment of attention by reward-associated cues

F Tashakori-Sabzevar, RD Ward - Frontiers in neuroscience, 2018 - frontiersin.org
The basal forebrain, composed of distributed nuclei, including substantia innominata (SI),
nucleus basalis and nucleus of the diagonal band of Broca plays a crucial neuromodulatory …

The granular retrosplenial cortex is necessary in male rats for object-location associative learning and memory, but not spatial working memory or visual discrimination …

PAS Sheppard, CA Oomen, TJ Bussey, LM Saksida - eneuro, 2024 - eneuro.org
The retrosplenial cortex (RSC) is a hub of diverse afferent and efferent projections thought to
be involved in associative learning. RSC shows early pathology in mild cognitive impairment …

Spared motivational modulation of cognitive effort in a maternal immune activation model of schizophrenia risk.

V Bates, A Maharjan, J Millar, DK Bilkey… - Behavioral …, 2018 - psycnet.apa.org
Maternal immune activation (MIA) during gestation is a significant risk factor for development
of schizophrenia and other neurodevelopmental diseases. In animal models of this risk …

The relationship between neuroticism and appetitive conditioning

T Klucken, O Kruse, S Klein, M Kampa, IT León… - … of Learning and …, 2019 - Elsevier
Appetitive conditioning is considered a central mechanism for the vulnerability to psychiatric
disorders. However, the investigation of individual differences that are related to altered …

The instrumental role of operant paradigms in translational psychiatric research: Insights from a maternal immune activation model of schizophrenia risk

AR Deane, RD Ward - Journal of the Experimental Analysis of …, 2022 - Wiley Online Library
Rigorous behavioral analysis is essential to the translation of research conducted using
animal models of neuropsychiatric disease. Here we discuss the use of operant paradigms …

Prediction of Cochlear Implant Effectiveness With Surface-Based Morphometry

S Minami, M Takahashi, S Shinden, K Shirai… - Otology & …, 2023 - journals.lww.com
Prediction of Cochlear Implant Effectiveness With Surface-Based Morphometry Page 1 Original
Study Prediction of Cochlear Implant Effectiveness With Surface-Based Morphometry *†Shujiro …

Chemogenetic Modulation of G Protein‐Coupled Receptor Signalling in Visual Attention Research

SH Jørgensen, CM Fitzpatrick, U Gether… - Basic & Clinical …, 2017 - Wiley Online Library
Attention is a fundamental cognitive process involved in nearly all aspects of life. Abnormal
attentional control is a symptom of many neurological disorders, most notably recognized in …