The study of genes mutated in human disease often leads to new insights into biology as
well as disease mechanisms. One such gene is Wilms' tumour 1 (WT1), which plays multiple …

Over the years, many apparently contradictory findings and functions have been ascribed to
the protein product of the WT1 tumour suppressor gene. These include being a …

BACKGROUND Pain remains the cardinal symptom of endometriosis. However, to date, the
underlying mechanisms are still only poorly understood. Increasing evidence points towards …

The WT1 (Wilms' tumour 1) gene encodes a zinc finger transcription factor and RNA-binding
protein that direct the development of several organs and tissues. WT1 manifests both …

The Wilms' tumor suppressor 1 (WT1) gene encodes a DNA-and RNA-binding protein that
plays an essential role in nephron progenitor differentiation during renal development. To …

The formation of intramyocardial blood vessels is critical for normal heart development and
tissue repair after infarction. We report here expression of the Wilms' tumor gene-1, Wt1, in …

WT1 was first described in 1990 as a tumour suppressor gene associated with Wilms tumour
(nephroblastoma). It encodes a typical transcription factor with four C2–H2 zinc fingers in the …

The Wilms' tumor suppressor gene Wt1 encodes a zinc-finger transcription factor that plays
an essential role in organ development, most notably of the kidney. Despite its importance …

The association of abnormal chromosome constitutions and disorders of sex development in
domestic animals has been recorded since the beginnings of conventional cytogenetic …

The Wilms' tumour suppressor protein, WT1, plays a central role in the development of the
genitourinary system and also other organs and tissues. WT1 can act as a transcriptional …