Shikonin and its derivatives, isolated from traditional medicinal plant species of the genus
Lithospermum, Alkanna, Arnebia, Anchusa, Onosma, and Echium belonging to the …

The naphthoquinone shikonin is the main active principle of Zicao, a traditional Chinese
herbal medicine made from the dried root of Lithospermum erythrorhizon. Studies carried …

Abstract Alkannin/shikonin (A/S) and their derivatives are naturally occurring
naphthoquinones majorly found in Boraginaceae family plants. They are integral …

Arnebiae Radix (dried root of Arnebia euchroma (Royle) Johnst.) has been used in
traditional Chinese medicine (TCM) to treat macular eruptions, measles, sore throat …

Shikonin is a naphthoquinone compound, generally extracted from the roots of the Oriental
medicinal herb Lithospermum erythrorhizon or the Indian medicinal herb Arnebia euchroma …

Osteosarcoma is the most common primary bone cancer that affects adolescents with early
metastatic potential and drastically reduces their long‐term survival rate if pulmonary …

Background and Purpose Overexpression or aberrant activation of the T‐lymphokine‐
activated killer cell‐originated protein kinase (TOPK) promotes gene expression and growth …

Quinones are plant-derived secondary metabolites that present diverse pharmacological
properties, including antibacterial, antifungal, antiviral, anti-inflammatory, antipyretic and …

Lithospermum officinale was used traditionally as a remedy in diseases of the urogenital
tract and as a spasmolytic, antidiarrhoeal, diuretic and lithotriptic, anti-gout, antitoxic …

Shikonin is one of the primary active components extracted from the dried root of Zicao
(Lithospermum erythrorhizon, Onosma paniculata, or Arnebia euchroma), a traditional …