Melatonin, dubbed the hormone of darkness, is known to regulate a wide variety of
physiological processes in mammals. This review describes well-defined functional …

The control of cancer, the second leading cause of death worldwide, may benefit from the
potential that resides in alternative therapies. The primary carcinogens stem from a variety of …

In addition to its antioxidative effects melatonin acts through specific nuclear and plasma
membrane receptors. To date, two G-protein coupled melatonin membrane receptors, MT1 …

The goals of this study were to determine (a) if melatonin enhances human adult
mesenchymal stem cell (hAMSC) differentiation into osteoblasts as assessed by measuring …

Purpose Melatonin is an amphipathic indolamine molecule ubiquitously present in all
organisms ranging from cyanobacteria to humans. The pineal gland is the site of melatonin …

Background: Although positive associations have consistently been reported between sleep
disruption and breast cancer, less is known about its potential role in prostate cancer …

Melatonin (MEL) is a hormone synthesized and secreted by the pineal gland deep within the
brain in response to photoperiodic cues relayed from the retina via an endogenous …

Melatonin inhibited the proliferation of hormone‐independent LNCaP prostate cancer cells
partly via MT1 receptor activation both in vitro and in nude mice xenograft model. In this …

Testicular germ cell tumors represent the most common malignancy among young men.
While 5-year overall survival and cure for this population is greater than 95 …

Reactive oxygen species (ROS) have been implicated in the pathogenesis of a variety of
diseases, and antioxidant treatment is currently being investigated as a potential therapy to …