[HTML][HTML] Oxidative stress in cancer

JD Hayes, AT Dinkova-Kostova, KD Tew - Cancer cell, 2020 - cell.com
Contingent upon concentration, reactive oxygen species (ROS) influence cancer evolution
in apparently contradictory ways, either initiating/stimulating tumorigenesis and supporting …

Stimuli-responsive polymer-based nanosystems for cancer theranostics

D Wei, Y Sun, H Zhu, Q Fu - ACS nano, 2023 - ACS Publications
Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …

Autonomous metal-organic framework nanorobots for active mitochondria-targeted cancer therapy

X Peng, S Tang, D Tang, D Zhou, Y Li, Q Chen… - Science …, 2023 - science.org
Nanorobotic manipulation to access subcellular organelles remains unmet due to the
challenge in achieving intracellular controlled propulsion. Intracellular organelles, such as …

Reactive oxygen species and cancer paradox: to promote or to suppress?

S Galadari, A Rahman, S Pallichankandy… - Free Radical Biology …, 2017 - Elsevier
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Short overview of ROS as cell function regulators and their implications in therapy concepts

L Milkovic, A Cipak Gasparovic, M Cindric, PA Mouthuy… - Cells, 2019 - mdpi.com
The importance of reactive oxygen species (ROS) has been gradually acknowledged over
the last four decades. Initially perceived as unwanted products of detrimental oxidative …

[HTML][HTML] Enzyme-triggered deep tumor penetration of a dual-drug nanomedicine enables an enhanced cancer combination therapy

L Gu, Z Duan, X Li, X Li, Y Li, X Li, G Xu, P Gao… - Bioactive Materials, 2023 - Elsevier
Cancer cells could be eradicated by promoting generation of excessive intracellular reactive
oxygen species (ROS) via emerging nanomedicines. However, tumor heterogeneity and …

[HTML][HTML] Photodynamic therapy combined with immunotherapy: Recent advances and future research directions

M Warszyńska, P Repetowski, JM Dąbrowski - Coordination Chemistry …, 2023 - Elsevier
Innovative anticancer therapies based on the activation of the immune system offer promise
in the battle against cancers resistant to traditional treatments. Examples of such therapeutic …

Concise review: emerging role of CD44 in cancer stem cells: a promising biomarker and therapeutic target

Y Yan, X Zuo, D Wei - Stem cells translational medicine, 2015 - academic.oup.com
The reception and integration of the plethora of signals a cell receives from its
microenvironment determines the cell's fate. CD44 functions as a receptor for hyaluronan …

Natural antioxidant evaluation: A review of detection methods

JS Mendonça, RCA Guimarães, VA Zorgetto-Pinheiro… - Molecules, 2022 - mdpi.com
Antioxidants have drawn the attention of the scientific community due to being related to the
prevention of various degenerative diseases. The antioxidant capacity has been extensively …

AMPK/FIS1-mediated mitophagy is required for self-renewal of human AML stem cells

S Pei, M Minhajuddin, B Adane, N Khan, BM Stevens… - Cell stem cell, 2018 - cell.com
Leukemia stem cells (LSCs) are thought to drive the genesis of acute myeloid leukemia
(AML) as well as relapse following chemotherapy. Because of their unique biology …