Underlying anticancer mechanisms and synergistic combinations of phytochemicals with cancer chemotherapeutics: potential benefits and risks

M Ayaz, A Nawaz, S Ahmad, OF Mosa… - Journal of Food …, 2022 - Wiley Online Library
Cancer therapies are associated with various challenges including the emergence of
multidrug resistant tumors, toxicological issues, severe side effects, and economic burden …

[HTML][HTML] Unveiling drimenol: a phytochemical with multifaceted bioactivities

Z Yang, KW Chan, MZ Abu Bakar, X Deng - Plants, 2024 - mdpi.com
Drimenol, a phytochemical with a distinct odor is found in edible aromatic plants, such as
Polygonum minus (known as kesum in Malaysia) and Drimys winteri. Recently, drimenol has …

Phytochemical Analysis, α‐Glucosidase and Amylase Inhibitory, and Molecular Docking Studies on Persicaria hydropiper L. Leaves Essential Oils

MH Mahnashi, YS Alqahtani, BA Alyami… - Evidence‐Based …, 2022 - Wiley Online Library
Objective. Medicinal plants and essentials oils are well known for diverse biological
activities including antidiabetic potential. This study was designed to isolate essential oils …

In-vitro, in-vivo, molecular docking and ADMET studies of 2-substituted 3, 7-dihydroxy-4H-chromen-4-one for oxidative stress, inflammation and Alzheimer's disease

MH Mahnashi, MA Alshahrani, MH Nahari, SS Hassan… - metabolites, 2022 - mdpi.com
Plants' bioactives are well-known safe drugs for vital diseases. Flavones and Flavonoid-rich
dietary supplements are known to exhibit neuroprotective potential. In this study, we isolated …

[HTML][HTML] Green seaweed Caulerpa racemosa-Chemical constituents, cytotoxicity in breast cancer cells and molecular docking simulation

G Sanger, D Wonggo, N Taher, V Dotulong… - Journal of Agriculture …, 2023 - Elsevier
Marine and terrestrial organisms are rich in chemical compounds with medicinal and
pharmacological properties, including antitumor agents for chemoprevention. Caulerpa …

Ephedra intermedia mediated synthesis of biogenic silver nanoparticles and their antimicrobial, cytotoxic and hemocompatability evaluations

MQ Nasar, M Shah, AT Khalil, MQ Kakar, M Ayaz… - Inorganic Chemistry …, 2022 - Elsevier
Biosynthesis, optimization, physicochemical properties and nanomedicinal applications of
the Ephedra intermedia Schrenk & CA Mey mediated silver nanoparticles (Et-AgNPs) has …

HPLC-DAD phenolics analysis, α-glucosidase, α-amylase inhibitory, molecular docking and nutritional profiles of Persicaria hydropiper L.

MH Mahnashi, YS Alqahtani, BA Alyami… - … Medicine and Therapies, 2022 - Springer
Background Natural phenolic compounds and Phenolics-rich medicinal plants are also of
great interest in the management of diabetes. The current study was aimed to analyze …

Green Nano‐Biotechnology: A New Sustainable Paradigm to Control Dengue Infection

T Zohra, AT Khalil, F Saeed, B Latif… - Bioinorganic …, 2022 - Wiley Online Library
Dengue is a growing mosquito‐borne viral disease prevalent in 128 countries, while 3.9
billion people are at high risk of acquiring the infection. With no specific treatment available …

Efficacy of 2-Hydroxyflavanone in rodent models of pain and inflammation: involvement of opioidergic and GABAergic anti-nociceptive mechanisms

FA Khan, G Ali, K Rahman, Y Khan, M Ayaz, OF Mosa… - Molecules, 2022 - mdpi.com
The current work examined the pharmacological potential of a selected flavanone derivative
2-hydroxyflavanone as a promising remedy for the treatment and management of pain. The …

Antioxidant, Enzyme Inhibitory, and Molecular Docking Approaches to the Antidiabetic Potentials of Bioactive Compounds from Persicaria hydropiper L.

M Ayaz, A Sadiq, OF Mosa, TA Zafar… - Evidence‐Based …, 2022 - Wiley Online Library
Introduction. Natural products are among the most useful sources for the discovery of new
drugs against various diseases. Kee** in view the ethnobotanical relevance …