Pseudogenes: pseudo-functional or key regulators in health and disease?
Pseudogenes have long been labeled as “junk” DNA, failed copies of genes that arise
during the evolution of genomes. However, recent results are challenging this moniker; …
during the evolution of genomes. However, recent results are challenging this moniker; …
Long non-coding RNAs: new players in plants
Z Zhao, S Zang, W Zou, YB Pan, W Yao, C You… - International Journal of …, 2022 - mdpi.com
During the process of growth and development, plants are prone to various biotic and abiotic
stresses. They have evolved a variety of strategies to resist the adverse effects of these …
stresses. They have evolved a variety of strategies to resist the adverse effects of these …
Human cancer long non-coding RNA transcriptomes
Once thought to be a part of the 'dark matter'of the genome, long non-coding RNAs
(lncRNAs) are emerging as an integral functional component of the mammalian …
(lncRNAs) are emerging as an integral functional component of the mammalian …
LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling
A Li, R Peng, Y Sun, H Liu, H Peng, Z Zhang - Cell death & disease, 2018 - nature.com
Long intergenic noncoding RNAs (lincRNAs) have been gradually identified to be functional
in a variety of different mechanisms associating with development and epigenetic regulation …
in a variety of different mechanisms associating with development and epigenetic regulation …
The passenger strand, miR-21-3p, plays a role in mediating cisplatin resistance in ovarian cancer cells
Objective Ovarian cancer is the deadliest gynaecological cancer. A major contributor to the
poor survival rate is the development of chemoresistance to platinum-based therapies such …
poor survival rate is the development of chemoresistance to platinum-based therapies such …
Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers
Background Molecular characterization of tumors has been critical for identifying important
genes in cancer biology and for improving tumor classification and diagnosis. Long non …
genes in cancer biology and for improving tumor classification and diagnosis. Long non …
LncRNA, miRNA and lncRNA-miRNA interaction in viral infection
L Chen, Y Zhou, H Li - Virus research, 2018 - Elsevier
Noncoding RNAs (ncRNAs) are key components of the transcriptome and play an important
role in both normal biological activity and pathological processes such as viral infection and …
role in both normal biological activity and pathological processes such as viral infection and …
Long noncoding RNA MEG3 interacts with p53 protein and regulates partial p53 target genes in hepatoma cells
J Zhu, S Liu, F Ye, Y Shen, Y Tie, J Zhu, L Wei, Y **… - PloS one, 2015 - journals.plos.org
Maternally Expressed Gene 3 (MEG3) encodes a lncRNA which is suggested to function as
a tumor suppressor. Previous studies suggested that MEG3 functioned through activation of …
a tumor suppressor. Previous studies suggested that MEG3 functioned through activation of …
Analysing the relationship between lnc RNA and protein‐coding gene and the role of lnc RNA as ce RNA in pulmonary fibrosis
X Song, G Cao, L **g, S Lin, X Wang… - Journal of cellular …, 2014 - Wiley Online Library
Long non‐coding RNA s (lnc RNA s) are involved in various pathophysiologic processes
and human diseases. However, their dynamics and corresponding functions in pulmonary …
and human diseases. However, their dynamics and corresponding functions in pulmonary …
Construction and comprehensive analysis of a ceRNA network to reveal potential prognostic biomarkers for hepatocellular carcinoma
Abstract Background Long noncoding RNAs (lncRNAs) can act as microRNA (miRNA)
sponges to regulate protein-coding gene expression; therefore, lncRNAs are considered a …
sponges to regulate protein-coding gene expression; therefore, lncRNAs are considered a …